Association of CCR5 del 32 with reduced risk of asthma

I P Hall, A Wheatley, G Christie, C McDougall, R Hubbard, P J Helms

Research output: Contribution to journalArticle

Abstract

We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.

Original languageEnglish
Pages (from-to)1264-1265
Number of pages2
JournalThe Lancet
Volume354
Publication statusPublished - 1999

Keywords

  • HIV-1 INFECTION
  • CHEMOKINES
  • GENE

Cite this

Hall, I. P., Wheatley, A., Christie, G., McDougall, C., Hubbard, R., & Helms, P. J. (1999). Association of CCR5 del 32 with reduced risk of asthma. The Lancet, 354, 1264-1265.

Association of CCR5 del 32 with reduced risk of asthma. / Hall, I P ; Wheatley, A ; Christie, G ; McDougall, C ; Hubbard, R ; Helms, P J .

In: The Lancet, Vol. 354, 1999, p. 1264-1265.

Research output: Contribution to journalArticle

Hall, IP, Wheatley, A, Christie, G, McDougall, C, Hubbard, R & Helms, PJ 1999, 'Association of CCR5 del 32 with reduced risk of asthma', The Lancet, vol. 354, pp. 1264-1265.
Hall IP, Wheatley A, Christie G, McDougall C, Hubbard R, Helms PJ. Association of CCR5 del 32 with reduced risk of asthma. The Lancet. 1999;354:1264-1265.
Hall, I P ; Wheatley, A ; Christie, G ; McDougall, C ; Hubbard, R ; Helms, P J . / Association of CCR5 del 32 with reduced risk of asthma. In: The Lancet. 1999 ; Vol. 354. pp. 1264-1265.
@article{54c1a38d139e484495c38e5d126618ee,
title = "Association of CCR5 del 32 with reduced risk of asthma",
abstract = "We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.",
keywords = "HIV-1 INFECTION, CHEMOKINES, GENE",
author = "Hall, {I P} and A Wheatley and G Christie and C McDougall and R Hubbard and Helms, {P J}",
year = "1999",
language = "English",
volume = "354",
pages = "1264--1265",
journal = "The Lancet",
issn = "0140-6736",
publisher = "ACADEMIC PRESS INC ELSEVIER SCIENCE",

}

TY - JOUR

T1 - Association of CCR5 del 32 with reduced risk of asthma

AU - Hall, I P

AU - Wheatley, A

AU - Christie, G

AU - McDougall, C

AU - Hubbard, R

AU - Helms, P J

PY - 1999

Y1 - 1999

N2 - We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.

AB - We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.

KW - HIV-1 INFECTION

KW - CHEMOKINES

KW - GENE

M3 - Article

VL - 354

SP - 1264

EP - 1265

JO - The Lancet

JF - The Lancet

SN - 0140-6736

ER -