Audit of an antibiotic policy and microbiological investigations for treating bacteraemia in a large teaching hospital.

A. R. Mackenzie, L. Robertson, B. Jappy, R. B. Laing, Ian M Gould

    Research output: Contribution to journalArticle

    11 Citations (Scopus)

    Abstract

    An audit of different approaches to guide empirical therapy in 78 cases of bacteraemia revealed poor utilisation of the antibiotic policy with resulting inadequate (P = 0.005) or excessive (P < 0.00001) antibiotic treatment and a trend to increased mortality. Eighty-seven percent of blood cultures were positive on Gram-stain within 24 h but streamlined therapy was still judged excessive in 27%. The results show poor utilisation of an up-to-date antibiotic policy but confirm its potential benefits and the ability of traditional culture methods to guide antibiotic therapy in a useful time-scale. (C) 2003 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

    Original languageEnglish
    Pages (from-to)618-621
    Number of pages3
    JournalInternational Journal of Antimicrobial Agents
    Volume22
    DOIs
    Publication statusPublished - 2003

    Keywords

    • antibiotic policy
    • bacteraemia
    • microbiological investigations
    • quality indicators
    • POSITIVE BLOOD CULTURES
    • CLINICAL IMPACT
    • IDENTIFICATION
    • RESISTANCE

    Cite this

    Audit of an antibiotic policy and microbiological investigations for treating bacteraemia in a large teaching hospital. / Mackenzie, A. R.; Robertson, L.; Jappy, B.; Laing, R. B.; Gould, Ian M.

    In: International Journal of Antimicrobial Agents, Vol. 22, 2003, p. 618-621.

    Research output: Contribution to journalArticle

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    AU - Gould, Ian M

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