Azole-Based Cyclic Peptides from the Sea Squirt Lissoclinum Patella: Old Scaffolds, New Avenues

Wael E Houssen; Marcel Jaspars

doi:10.1002/cbic.201000230

Azole-Based Cyclic Peptides from the Sea Squirt Lissoclinum Patella: Old Scaffolds, New Avenues

Wael E Houssen, Marcel Jaspars

Research output: Contribution to journal › Literature review › peer-review

41 Citations (Scopus)

Abstract

A combinatorial library encoded on a single gene: Azole-based cyclic peptides identified from the marine ascidian Lissoclinum patella are produced by its cyanobacterial symbiont Prochloron sp. through a ribosomal pathway. Variants of a single gene within the biosynthetic cluster led to different products.

Original language	English
Pages (from-to)	1803-1815
Number of pages	13
Journal	ChemBioChem
Volume	11
Issue number	13
Early online date	15 Jul 2010
DOIs	https://doi.org/10.1002/cbic.201000230
Publication status	Published - 3 Sept 2010

Keywords

biological activity
biosynthesis
cyclic peptides
heterocycles
peptides

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/cbic.201000230

Cite this

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abstract = "A combinatorial library encoded on a single gene: Azole-based cyclic peptides identified from the marine ascidian Lissoclinum patella are produced by its cyanobacterial symbiont Prochloron sp. through a ribosomal pathway. Variants of a single gene within the biosynthetic cluster led to different products. ",

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T2 - Old Scaffolds, New Avenues

AU - Houssen, Wael E

AU - Jaspars, Marcel

PY - 2010/9/3

Y1 - 2010/9/3

N2 - A combinatorial library encoded on a single gene: Azole-based cyclic peptides identified from the marine ascidian Lissoclinum patella are produced by its cyanobacterial symbiont Prochloron sp. through a ribosomal pathway. Variants of a single gene within the biosynthetic cluster led to different products.

AB - A combinatorial library encoded on a single gene: Azole-based cyclic peptides identified from the marine ascidian Lissoclinum patella are produced by its cyanobacterial symbiont Prochloron sp. through a ribosomal pathway. Variants of a single gene within the biosynthetic cluster led to different products.

KW - biological activity

KW - biosynthesis

KW - cyclic peptides

KW - heterocycles

KW - peptides

U2 - 10.1002/cbic.201000230

DO - 10.1002/cbic.201000230

M3 - Literature review

SN - 1439-4227

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SP - 1803

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JO - ChemBioChem

JF - ChemBioChem

IS - 13

ER -

Azole-Based Cyclic Peptides from the Sea Squirt Lissoclinum Patella: Old Scaffolds, New Avenues

Abstract

Keywords

UN SDGs

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