Azole-Based Cyclic Peptides from the Sea Squirt Lissoclinum Patella: Old Scaffolds, New Avenues

Research output: Contribution to journalLiterature review

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Abstract

A combinatorial library encoded on a single gene: Azole-based cyclic peptides identified from the marine ascidian Lissoclinum patella are produced by its cyanobacterial symbiont Prochloron sp. through a ribosomal pathway. Variants of a single gene within the biosynthetic cluster led to different products.
Original languageEnglish
Pages (from-to)1803-1815
Number of pages13
JournalChemBioChem
Volume11
Issue number13
Early online date15 Jul 2010
DOIs
Publication statusPublished - 3 Sep 2010

Keywords

  • biological activity
  • biosynthesis
  • cyclic peptides
  • heterocycles
  • peptides

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