Bioactive flavonoid glycosides from the seeds of Rosa canina

Y Kumarasamy, P J Cox, M Jaspars, M A Rashid, S D Sarker

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Preparative RP-HPLC analysis of a methanol extract of the seeds of Rosa canina yielded kaempferol 3-O-(6"-O-E-p-coumaroyl)-beta-D-glucopyranoside and kaempferol 3-O-(6"=O-Z-p-coumaroyl)-beta-D-glucopyranoside. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. Bioactivity, i.e., antibacterial and antioxidant activity and general toxicity, of these compounds were also determined.

Original languageEnglish
Pages (from-to)237-242
Number of pages6
JournalPharmaceutical Biology
Volume41
Publication statusPublished - 2003

Keywords

  • Rosa canina
  • Rosaceae
  • astragalin
  • kaempferol tiliroside
  • brine shrimp
  • lethality bioassay
  • DPPH assay
  • antibacterial assay
  • NMR
  • CHEMICAL-CONSTITUENTS
  • EXTRACT

Cite this

Kumarasamy, Y., Cox, P. J., Jaspars, M., Rashid, M. A., & Sarker, S. D. (2003). Bioactive flavonoid glycosides from the seeds of Rosa canina. Pharmaceutical Biology, 41, 237-242.