Bioactive flavonoid glycosides from the seeds of Rosa canina

Y  Kumarasamy; P J  Cox; M  Jaspars; M A  Rashid; S D  Sarker

Bioactive flavonoid glycosides from the seeds of Rosa canina

Y Kumarasamy, P J Cox, M Jaspars, M A Rashid, S D Sarker

Chemistry

Research output: Contribution to journal › Article

31 Citations (Scopus)

Abstract

Preparative RP-HPLC analysis of a methanol extract of the seeds of Rosa canina yielded kaempferol 3-O-(6"-O-E-p-coumaroyl)-beta-D-glucopyranoside and kaempferol 3-O-(6"=O-Z-p-coumaroyl)-beta-D-glucopyranoside. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. Bioactivity, i.e., antibacterial and antioxidant activity and general toxicity, of these compounds were also determined.

Original language	English
Pages (from-to)	237-242
Number of pages	6
Journal	Pharmaceutical Biology
Volume	41
Publication status	Published - 2003

Keywords

Rosa canina
Rosaceae
astragalin
kaempferol tiliroside
brine shrimp
lethality bioassay
DPPH assay
antibacterial assay
NMR
CHEMICAL-CONSTITUENTS
EXTRACT

Cite this

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title = "Bioactive flavonoid glycosides from the seeds of Rosa canina",

abstract = "Preparative RP-HPLC analysis of a methanol extract of the seeds of Rosa canina yielded kaempferol 3-O-(6{"}-O-E-p-coumaroyl)-beta-D-glucopyranoside and kaempferol 3-O-(6{"}=O-Z-p-coumaroyl)-beta-D-glucopyranoside. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. Bioactivity, i.e., antibacterial and antioxidant activity and general toxicity, of these compounds were also determined.",

keywords = "Rosa canina, Rosaceae, astragalin, kaempferol tiliroside, brine shrimp, lethality bioassay, DPPH assay, antibacterial assay, NMR, CHEMICAL-CONSTITUENTS, EXTRACT",

author = "Y Kumarasamy and Cox, {P J} and M Jaspars and Rashid, {M A} and Sarker, {S D}",

year = "2003",

language = "English",

volume = "41",

pages = "237--242",

journal = "Pharmaceutical Biology",

issn = "1388-0209",

publisher = "Informa Healthcare",

}

TY - JOUR

T1 - Bioactive flavonoid glycosides from the seeds of Rosa canina

AU - Kumarasamy, Y

AU - Cox, P J

AU - Jaspars, M

AU - Rashid, M A

AU - Sarker, S D

PY - 2003

Y1 - 2003

N2 - Preparative RP-HPLC analysis of a methanol extract of the seeds of Rosa canina yielded kaempferol 3-O-(6"-O-E-p-coumaroyl)-beta-D-glucopyranoside and kaempferol 3-O-(6"=O-Z-p-coumaroyl)-beta-D-glucopyranoside. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. Bioactivity, i.e., antibacterial and antioxidant activity and general toxicity, of these compounds were also determined.

AB - Preparative RP-HPLC analysis of a methanol extract of the seeds of Rosa canina yielded kaempferol 3-O-(6"-O-E-p-coumaroyl)-beta-D-glucopyranoside and kaempferol 3-O-(6"=O-Z-p-coumaroyl)-beta-D-glucopyranoside. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. Bioactivity, i.e., antibacterial and antioxidant activity and general toxicity, of these compounds were also determined.

KW - Rosa canina

KW - Rosaceae

KW - astragalin

KW - kaempferol tiliroside

KW - brine shrimp

KW - lethality bioassay

KW - DPPH assay

KW - antibacterial assay

KW - NMR

KW - CHEMICAL-CONSTITUENTS

KW - EXTRACT

M3 - Article

VL - 41

SP - 237

EP - 242

JO - Pharmaceutical Biology

JF - Pharmaceutical Biology

SN - 1388-0209

ER -

Bioactive flavonoid glycosides from the seeds of Rosa canina

Abstract

Keywords

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