Abstract
Preparative RP-HPLC analysis of a methanol extract of the seeds of Rosa canina yielded kaempferol 3-O-(6"-O-E-p-coumaroyl)-beta-D-glucopyranoside and kaempferol 3-O-(6"=O-Z-p-coumaroyl)-beta-D-glucopyranoside. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. Bioactivity, i.e., antibacterial and antioxidant activity and general toxicity, of these compounds were also determined.
| Original language | English |
|---|---|
| Pages (from-to) | 237-242 |
| Number of pages | 6 |
| Journal | Pharmaceutical Biology |
| Volume | 41 |
| Publication status | Published - 2003 |
Keywords
- Rosa canina
- Rosaceae
- astragalin
- kaempferol tiliroside
- brine shrimp
- lethality bioassay
- DPPH assay
- antibacterial assay
- NMR
- CHEMICAL-CONSTITUENTS
- EXTRACT
Cite this
Kumarasamy, Y., Cox, P. J., Jaspars, M., Rashid, M. A., & Sarker, S. D. (2003). Bioactive flavonoid glycosides from the seeds of Rosa canina. Pharmaceutical Biology, 41, 237-242.