Bioactive flavonoid glycosides from the seeds of Rosa canina

Y Kumarasamy, P J Cox, M Jaspars, M A Rashid, S D Sarker

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Preparative RP-HPLC analysis of a methanol extract of the seeds of Rosa canina yielded kaempferol 3-O-(6"-O-E-p-coumaroyl)-beta-D-glucopyranoside and kaempferol 3-O-(6"=O-Z-p-coumaroyl)-beta-D-glucopyranoside. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. Bioactivity, i.e., antibacterial and antioxidant activity and general toxicity, of these compounds were also determined.

Original languageEnglish
Pages (from-to)237-242
Number of pages6
JournalPharmaceutical Biology
Volume41
Publication statusPublished - 2003

Keywords

  • Rosa canina
  • Rosaceae
  • astragalin
  • kaempferol tiliroside
  • brine shrimp
  • lethality bioassay
  • DPPH assay
  • antibacterial assay
  • NMR
  • CHEMICAL-CONSTITUENTS
  • EXTRACT

Cite this

Kumarasamy, Y., Cox, P. J., Jaspars, M., Rashid, M. A., & Sarker, S. D. (2003). Bioactive flavonoid glycosides from the seeds of Rosa canina. Pharmaceutical Biology, 41, 237-242.

Bioactive flavonoid glycosides from the seeds of Rosa canina. / Kumarasamy, Y ; Cox, P J ; Jaspars, M ; Rashid, M A ; Sarker, S D .

In: Pharmaceutical Biology, Vol. 41, 2003, p. 237-242.

Research output: Contribution to journalArticle

Kumarasamy, Y, Cox, PJ, Jaspars, M, Rashid, MA & Sarker, SD 2003, 'Bioactive flavonoid glycosides from the seeds of Rosa canina', Pharmaceutical Biology, vol. 41, pp. 237-242.
Kumarasamy Y, Cox PJ, Jaspars M, Rashid MA, Sarker SD. Bioactive flavonoid glycosides from the seeds of Rosa canina. Pharmaceutical Biology. 2003;41:237-242.
Kumarasamy, Y ; Cox, P J ; Jaspars, M ; Rashid, M A ; Sarker, S D . / Bioactive flavonoid glycosides from the seeds of Rosa canina. In: Pharmaceutical Biology. 2003 ; Vol. 41. pp. 237-242.
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