Bioactivity of Hirsutanolol, Oregonin and Genkwanin, Isolated from the Seeds of Alnus glutinosa (Betulaceae)

Y. Kumarasamy, P. J. Cox, Marcel Jaspars, L. Nahar, S. D. Sarker

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Abstract

The antibacterial and free radical scavenging activity, and the general toxicity of two diarylheptanoids, hirsutanolol (1) and oregonin (2), and a flavonoid, genkwanin (3), isolated from the methanol extract of the seeds of Alnus glutinosa, were assessed by the 96 well-based serial dilution antibacterial assay using resazurin as an indicator of cell growth, the DPPH assay, and the brine shrimp lethality assay, respectively.

Original languageEnglish
Pages (from-to)641-644
Number of pages3
JournalNatural Product Communications
Volume1
Issue number8
Publication statusPublished - 2006

Keywords

  • Alnus glutinosa
  • betulaceae
  • hirsutanolol
  • oregonin
  • genkwanin
  • antibacterial
  • antioxidant
  • DPPH
  • brine shrimp lethality assay
  • STRUCTURE ELUCIDATION
  • FEMALE FLOWERS
  • GLYCOSIDES
  • SERRULATOIDES

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