Bioactivity of Hirsutanolol, Oregonin and Genkwanin, Isolated from the Seeds of Alnus glutinosa (Betulaceae)

Y. Kumarasamy; P. J. Cox; Marcel Jaspars; L. Nahar; S. D. Sarker

Bioactivity of Hirsutanolol, Oregonin and Genkwanin, Isolated from the Seeds of Alnus glutinosa (Betulaceae)

Y. Kumarasamy, P. J. Cox, Marcel Jaspars, L. Nahar, S. D. Sarker

Chemistry

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

The antibacterial and free radical scavenging activity, and the general toxicity of two diarylheptanoids, hirsutanolol (1) and oregonin (2), and a flavonoid, genkwanin (3), isolated from the methanol extract of the seeds of Alnus glutinosa, were assessed by the 96 well-based serial dilution antibacterial assay using resazurin as an indicator of cell growth, the DPPH assay, and the brine shrimp lethality assay, respectively.

Original language	English
Pages (from-to)	641-644
Number of pages	3
Journal	Natural Product Communications
Volume	1
Issue number	8
Publication status	Published - 2006

Keywords

Alnus glutinosa
betulaceae
hirsutanolol
oregonin
genkwanin
antibacterial
antioxidant
DPPH
brine shrimp lethality assay
STRUCTURE ELUCIDATION
FEMALE FLOWERS
GLYCOSIDES
SERRULATOIDES

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title = "Bioactivity of Hirsutanolol, Oregonin and Genkwanin, Isolated from the Seeds of Alnus glutinosa (Betulaceae)",

abstract = "The antibacterial and free radical scavenging activity, and the general toxicity of two diarylheptanoids, hirsutanolol (1) and oregonin (2), and a flavonoid, genkwanin (3), isolated from the methanol extract of the seeds of Alnus glutinosa, were assessed by the 96 well-based serial dilution antibacterial assay using resazurin as an indicator of cell growth, the DPPH assay, and the brine shrimp lethality assay, respectively.",

keywords = "Alnus glutinosa, betulaceae, hirsutanolol, oregonin, genkwanin, antibacterial, antioxidant, DPPH, brine shrimp lethality assay, STRUCTURE ELUCIDATION, FEMALE FLOWERS, GLYCOSIDES, SERRULATOIDES",

author = "Y. Kumarasamy and Cox, {P. J.} and Marcel Jaspars and L. Nahar and Sarker, {S. D.}",

year = "2006",

language = "English",

volume = "1",

pages = "641--644",

journal = "Natural Product Communications",

issn = "1934-578X",

publisher = "Natural Product Communications",

number = "8",

}

TY - JOUR

T1 - Bioactivity of Hirsutanolol, Oregonin and Genkwanin, Isolated from the Seeds of Alnus glutinosa (Betulaceae)

AU - Kumarasamy, Y.

AU - Cox, P. J.

AU - Jaspars, Marcel

AU - Nahar, L.

AU - Sarker, S. D.

PY - 2006

Y1 - 2006

N2 - The antibacterial and free radical scavenging activity, and the general toxicity of two diarylheptanoids, hirsutanolol (1) and oregonin (2), and a flavonoid, genkwanin (3), isolated from the methanol extract of the seeds of Alnus glutinosa, were assessed by the 96 well-based serial dilution antibacterial assay using resazurin as an indicator of cell growth, the DPPH assay, and the brine shrimp lethality assay, respectively.

AB - The antibacterial and free radical scavenging activity, and the general toxicity of two diarylheptanoids, hirsutanolol (1) and oregonin (2), and a flavonoid, genkwanin (3), isolated from the methanol extract of the seeds of Alnus glutinosa, were assessed by the 96 well-based serial dilution antibacterial assay using resazurin as an indicator of cell growth, the DPPH assay, and the brine shrimp lethality assay, respectively.

KW - Alnus glutinosa

KW - betulaceae

KW - hirsutanolol

KW - oregonin

KW - genkwanin

KW - antibacterial

KW - antioxidant

KW - DPPH

KW - brine shrimp lethality assay

KW - STRUCTURE ELUCIDATION

KW - FEMALE FLOWERS

KW - GLYCOSIDES

KW - SERRULATOIDES

M3 - Article

SN - 1934-578X

VL - 1

SP - 641

EP - 644

JO - Natural Product Communications

JF - Natural Product Communications

IS - 8

ER -

Bioactivity of Hirsutanolol, Oregonin and Genkwanin, Isolated from the Seeds of Alnus glutinosa (Betulaceae)

Abstract

Keywords

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