We discovered and characterised a novel fluorinating enzyme from marine-derived bacterium Streptomyces xinghaiensis, this is the first ever fluorinase unveiled from marine source. It is also the ‘fastest’ fluorinase by far, which promises to be useful for bio-diagnostic and industrial purposes such as PET radiotracer labeling, fluorinated bio-transformation and synthetic biology.
- marine organisms
Ma, L., Li, Y., Meng, L., Deng, H., Li, Y., Zhang, Q., & Diao, A. (2016). Biological fluorination from the sea: discovery of a SAM-dependent nucleophilic fluorinating enzyme from the marine-derived bacterium Streptomyces xinghaiensis NRRL B24674. RSC Advances, 32(6), 27047-27051. https://doi.org/10.1039/C6RA00100A