Blood and urine acid-base status of premenopausal omnivorous and vegetarian women

D. Ball*, R. J. Maughan

*Corresponding author for this work

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The effect of long-term differences in diet composition on whole-body acid-base status was examined in thirty-three young healthy females. The volunteers were recruited from two separate groups matched approximately for age, height and weight; one group regularly ate meat (omnivores; n 20) and one group did not (vegetarians; n 13). All subjects completed a 7 d weighed intake of food, and from their dietary records, total energy, carbohydrate (CHO), fat and protein content were estimated using computer-based food composition tables. During this week they reported to the laboratory on two occasions, following an overnight fast and separated by at least 48 h. Arterialized venous blood samples were obtained on each visit and these were analysed for blood acid-base status. Haemoglobin and packed cell volume, serum total cholesterol and HDL-cholesterol, serum albumin and total protein were also determined. Two 24 h urine collections were completed; the volume was recorded and samples were analysed for pH, titratable acid and Mg and Ca concentration. Total energy intake of the omnivores was greater (P = 0.0003) than that of the vegetarian group. Dietary intake of CHO (P = 0.024), fat (P = 0.0054) and protein (P = 0.0002) were higher in the omnivorous group than in the vegetarians. There were no differences between the two groups with respect to blood CO2 partial pressure, plasma HCO3 - and blood base excess, but blood pH was slightly higher in the omnivores (P = 0.064). Measures of urine acid-base status suggested a lower pH in the omnivore group, but this difference was not statistically significant; a greater titratable acid output was observed with the omnivorous group compared with the vegetarians (48.9 (SE 20.3) v 35.3 (SE 23.3) mEq/24 h; P = 0.018). Although the dietary intake of Ca was not different between the two groups, urinary Ca excretion of the omnivores was significantly higher (3.87 (so 1.34) v. 3.22 (SD 1.20) mmol/24 h) than that of the vegetarians (P = 0.014). It is suggested that the higher protein intake of the omnivores resulted in an increase in urinary total acid excretion, which may explain the higher rate of Ca excretion.

Original languageEnglish
Pages (from-to)683-693
Number of pages11
JournalBritish Journal of Nutrition
Volume78
Issue number5
DOIs
Publication statusPublished - Nov 1997

Fingerprint

Urine
Acids
Proteins
Fats
Diet Records
Urine Specimen Collection
Partial Pressure
Energy Intake
Cell Size
Serum Albumin
Meat
HDL Cholesterol
Vegetarians
Volunteers
Hemoglobins
Research Design
Eating
Cholesterol
Carbohydrates
Diet

Keywords

  • Acid-base status
  • Calcium
  • Omnivores
  • Titratable acid output
  • Vegetarians

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

Blood and urine acid-base status of premenopausal omnivorous and vegetarian women. / Ball, D.; Maughan, R. J.

In: British Journal of Nutrition, Vol. 78, No. 5, 11.1997, p. 683-693.

Research output: Contribution to journalArticle

@article{f2a4584dcea8452d8e794aa4dc350e7a,
title = "Blood and urine acid-base status of premenopausal omnivorous and vegetarian women",
abstract = "The effect of long-term differences in diet composition on whole-body acid-base status was examined in thirty-three young healthy females. The volunteers were recruited from two separate groups matched approximately for age, height and weight; one group regularly ate meat (omnivores; n 20) and one group did not (vegetarians; n 13). All subjects completed a 7 d weighed intake of food, and from their dietary records, total energy, carbohydrate (CHO), fat and protein content were estimated using computer-based food composition tables. During this week they reported to the laboratory on two occasions, following an overnight fast and separated by at least 48 h. Arterialized venous blood samples were obtained on each visit and these were analysed for blood acid-base status. Haemoglobin and packed cell volume, serum total cholesterol and HDL-cholesterol, serum albumin and total protein were also determined. Two 24 h urine collections were completed; the volume was recorded and samples were analysed for pH, titratable acid and Mg and Ca concentration. Total energy intake of the omnivores was greater (P = 0.0003) than that of the vegetarian group. Dietary intake of CHO (P = 0.024), fat (P = 0.0054) and protein (P = 0.0002) were higher in the omnivorous group than in the vegetarians. There were no differences between the two groups with respect to blood CO2 partial pressure, plasma HCO3 - and blood base excess, but blood pH was slightly higher in the omnivores (P = 0.064). Measures of urine acid-base status suggested a lower pH in the omnivore group, but this difference was not statistically significant; a greater titratable acid output was observed with the omnivorous group compared with the vegetarians (48.9 (SE 20.3) v 35.3 (SE 23.3) mEq/24 h; P = 0.018). Although the dietary intake of Ca was not different between the two groups, urinary Ca excretion of the omnivores was significantly higher (3.87 (so 1.34) v. 3.22 (SD 1.20) mmol/24 h) than that of the vegetarians (P = 0.014). It is suggested that the higher protein intake of the omnivores resulted in an increase in urinary total acid excretion, which may explain the higher rate of Ca excretion.",
keywords = "Acid-base status, Calcium, Omnivores, Titratable acid output, Vegetarians",
author = "D. Ball and Maughan, {R. J.}",
year = "1997",
month = "11",
doi = "10.1079/BJN19970187",
language = "English",
volume = "78",
pages = "683--693",
journal = "British Journal of Nutrition",
issn = "0007-1145",
publisher = "Cambridge Univ. Press.",
number = "5",

}

TY - JOUR

T1 - Blood and urine acid-base status of premenopausal omnivorous and vegetarian women

AU - Ball, D.

AU - Maughan, R. J.

PY - 1997/11

Y1 - 1997/11

N2 - The effect of long-term differences in diet composition on whole-body acid-base status was examined in thirty-three young healthy females. The volunteers were recruited from two separate groups matched approximately for age, height and weight; one group regularly ate meat (omnivores; n 20) and one group did not (vegetarians; n 13). All subjects completed a 7 d weighed intake of food, and from their dietary records, total energy, carbohydrate (CHO), fat and protein content were estimated using computer-based food composition tables. During this week they reported to the laboratory on two occasions, following an overnight fast and separated by at least 48 h. Arterialized venous blood samples were obtained on each visit and these were analysed for blood acid-base status. Haemoglobin and packed cell volume, serum total cholesterol and HDL-cholesterol, serum albumin and total protein were also determined. Two 24 h urine collections were completed; the volume was recorded and samples were analysed for pH, titratable acid and Mg and Ca concentration. Total energy intake of the omnivores was greater (P = 0.0003) than that of the vegetarian group. Dietary intake of CHO (P = 0.024), fat (P = 0.0054) and protein (P = 0.0002) were higher in the omnivorous group than in the vegetarians. There were no differences between the two groups with respect to blood CO2 partial pressure, plasma HCO3 - and blood base excess, but blood pH was slightly higher in the omnivores (P = 0.064). Measures of urine acid-base status suggested a lower pH in the omnivore group, but this difference was not statistically significant; a greater titratable acid output was observed with the omnivorous group compared with the vegetarians (48.9 (SE 20.3) v 35.3 (SE 23.3) mEq/24 h; P = 0.018). Although the dietary intake of Ca was not different between the two groups, urinary Ca excretion of the omnivores was significantly higher (3.87 (so 1.34) v. 3.22 (SD 1.20) mmol/24 h) than that of the vegetarians (P = 0.014). It is suggested that the higher protein intake of the omnivores resulted in an increase in urinary total acid excretion, which may explain the higher rate of Ca excretion.

AB - The effect of long-term differences in diet composition on whole-body acid-base status was examined in thirty-three young healthy females. The volunteers were recruited from two separate groups matched approximately for age, height and weight; one group regularly ate meat (omnivores; n 20) and one group did not (vegetarians; n 13). All subjects completed a 7 d weighed intake of food, and from their dietary records, total energy, carbohydrate (CHO), fat and protein content were estimated using computer-based food composition tables. During this week they reported to the laboratory on two occasions, following an overnight fast and separated by at least 48 h. Arterialized venous blood samples were obtained on each visit and these were analysed for blood acid-base status. Haemoglobin and packed cell volume, serum total cholesterol and HDL-cholesterol, serum albumin and total protein were also determined. Two 24 h urine collections were completed; the volume was recorded and samples were analysed for pH, titratable acid and Mg and Ca concentration. Total energy intake of the omnivores was greater (P = 0.0003) than that of the vegetarian group. Dietary intake of CHO (P = 0.024), fat (P = 0.0054) and protein (P = 0.0002) were higher in the omnivorous group than in the vegetarians. There were no differences between the two groups with respect to blood CO2 partial pressure, plasma HCO3 - and blood base excess, but blood pH was slightly higher in the omnivores (P = 0.064). Measures of urine acid-base status suggested a lower pH in the omnivore group, but this difference was not statistically significant; a greater titratable acid output was observed with the omnivorous group compared with the vegetarians (48.9 (SE 20.3) v 35.3 (SE 23.3) mEq/24 h; P = 0.018). Although the dietary intake of Ca was not different between the two groups, urinary Ca excretion of the omnivores was significantly higher (3.87 (so 1.34) v. 3.22 (SD 1.20) mmol/24 h) than that of the vegetarians (P = 0.014). It is suggested that the higher protein intake of the omnivores resulted in an increase in urinary total acid excretion, which may explain the higher rate of Ca excretion.

KW - Acid-base status

KW - Calcium

KW - Omnivores

KW - Titratable acid output

KW - Vegetarians

UR - http://www.scopus.com/inward/record.url?scp=0030856276&partnerID=8YFLogxK

U2 - 10.1079/BJN19970187

DO - 10.1079/BJN19970187

M3 - Article

C2 - 9389893

AN - SCOPUS:0030856276

VL - 78

SP - 683

EP - 693

JO - British Journal of Nutrition

JF - British Journal of Nutrition

SN - 0007-1145

IS - 5

ER -