Blood antioxidant status and plasma pyruvate kinase activity of halothane-reacting pigs

Garry G. Duthie, John Arthur

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Abstract

Samples of blood were collected (by jugular venipuncture) from 10 homozygote halothane-reacting pigs and 7 homozygote nonreactors. Antioxidant status was assessed by measurement of blood glutathione peroxidase, glucose-6-phosphate dehydrogenase, and superoxide dismutase activities and plasma concentrations of vitamin E. Significant differences in these values were not apparent between halothane-reacting pigs and nonreactors. Halothane-reacting pigs had tissue damage as indicated by significantly increased plasma activities of the enzymes creatine kinase and pyruvate kinase. The latter showed better discrimination between the 2 populations than did creatine kinase and could prove to be a more effective marker for identification of stress-susceptible pigs.
Original languageEnglish
Pages (from-to)309-310
Number of pages2
JournalAmerican Journal of Veterinary Research
Volume48
Issue number2
Publication statusPublished - Feb 1987

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