Candida albicans and Candida dubliniensis respond differently to echinocandin antifungal agents in vitro

Mette D. Jacobsen, Julie A. Whyte, Frank Christopher Odds

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Candida dubliniensis isolates tested for susceptibility to anidulafungin, caspofungin, and micafungin commonly showed artifactual regrowth and/or trailing effects with MIC tests done under conditions involving a high initial yeast concentration. The artifacts were less common with Candida albicans and seldom seen for either species under Clinical and Laboratory Standards Institute method M27-A test conditions.

Original languageEnglish
Pages (from-to)1882-1884
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume51
Issue number5
Early online date16 Feb 2007
DOIs
Publication statusPublished - May 2007

Keywords

  • high drug concentrations
  • caspofungin
  • fluconazole
  • virulence
  • gene

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