Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion

Heping Xu, Mei Chen, John V Forrester, Noemi Lois

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

To investigate the effect(s) of cataract surgery on the expression of pro-inflammatory genes and proteins in the retina using an experimental rodent model.
Original languageEnglish
Pages (from-to)249-255
Number of pages7
JournalInvestigative Ophthalmology & Visual Science
Volume52
Issue number1
Early online date18 Aug 2010
DOIs
Publication statusPublished - 5 Jan 2011

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Keywords

  • Animals
  • Cataract Extraction
  • Chemokine CCL2
  • Chemokine CXCL12
  • Choroid
  • Complement System Proteins
  • Cytokines
  • Fibroblast Growth Factors
  • Fluorescent Antibody Technique, Indirect
  • Gene Expression Regulation
  • Interleukin-1beta
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Microscopy, Confocal
  • Retina
  • Retinal Pigment Epithelium
  • Reverse Transcriptase Polymerase Chain Reaction
  • Transforming Growth Factor beta

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