Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion

Heping Xu; Mei Chen; John V Forrester; Noemi Lois

doi:10.1167/iovs.10-6001

Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion

Heping Xu, Mei Chen, John V Forrester, Noemi Lois

Applied Medicine

Research output: Contribution to journal › Article › peer-review

107 Citations (Scopus)

Abstract

To investigate the effect(s) of cataract surgery on the expression of pro-inflammatory genes and proteins in the retina using an experimental rodent model.

Original language	English
Pages (from-to)	249-255
Number of pages	7
Journal	Investigative Ophthalmology & Visual Science
Volume	52
Issue number	1
Early online date	18 Aug 2010
DOIs	https://doi.org/10.1167/iovs.10-6001
Publication status	Published - 5 Jan 2011

Keywords

Animals
Cataract Extraction
Chemokine CCL2
Chemokine CXCL12
Choroid
Complement System Proteins
Cytokines
Fibroblast Growth Factors
Fluorescent Antibody Technique, Indirect
Gene Expression Regulation
Interleukin-1beta
Male
Mice
Mice, Inbred C57BL
Microscopy, Confocal
Retina
Retinal Pigment Epithelium
Reverse Transcriptase Polymerase Chain Reaction
Transforming Growth Factor beta

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title = "Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion",

abstract = "To investigate the effect(s) of cataract surgery on the expression of pro-inflammatory genes and proteins in the retina using an experimental rodent model.",

keywords = "Animals, Cataract Extraction, Chemokine CCL2, Chemokine CXCL12, Choroid, Complement System Proteins, Cytokines, Fibroblast Growth Factors, Fluorescent Antibody Technique, Indirect, Gene Expression Regulation, Interleukin-1beta, Male, Mice, Mice, Inbred C57BL, Microscopy, Confocal, Retina, Retinal Pigment Epithelium, Reverse Transcriptase Polymerase Chain Reaction, Transforming Growth Factor beta",

author = "Heping Xu and Mei Chen and Forrester, {John V} and Noemi Lois",

year = "2011",

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doi = "10.1167/iovs.10-6001",

language = "English",

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AU - Chen, Mei

AU - Forrester, John V

AU - Lois, Noemi

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N2 - To investigate the effect(s) of cataract surgery on the expression of pro-inflammatory genes and proteins in the retina using an experimental rodent model.

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KW - Chemokine CCL2

KW - Chemokine CXCL12

KW - Choroid

KW - Complement System Proteins

KW - Cytokines

KW - Fibroblast Growth Factors

KW - Fluorescent Antibody Technique, Indirect

KW - Gene Expression Regulation

KW - Interleukin-1beta

KW - Male

KW - Mice

KW - Mice, Inbred C57BL

KW - Microscopy, Confocal

KW - Retina

KW - Retinal Pigment Epithelium

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Transforming Growth Factor beta

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DO - 10.1167/iovs.10-6001

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EP - 255

JO - Investigative Ophthalmology & Visual Science

JF - Investigative Ophthalmology & Visual Science

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ER -

Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion

Abstract

Keywords

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