Abstract
CD8 cells from human immunodeficiency virus (HIV)-infected adults and children can show cytotoxic as well as noncytotoxic activity against viral replication. The noncytotoxic anti-HIV response, measured by suppression of acute vital infection of CD4 cells, has also been observed in uninfected adults who have a history of exposure to HIV. This CD8 cell antiviral activity was found to be detectable as well in ~50% of uninfected children born of infected mothers. The findings could reflect a protective response of the children to HIV after being exposed to the virus.
Original language | English |
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Pages (from-to) | 470-472 |
Number of pages | 3 |
Journal | Journal of Infectious Diseases |
Volume | 177 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1998 |