Abstract
In this paper we argue that the effects of irregular chaotic motion of particles transported by blood can play a major role in the development of serious circulatory diseases. Vessel wall irregularities modify the flow field, changing in a nontrivial way the transport and activation of biochemically active particles. We argue that blood particle transport is often chaotic in realistic physiological conditions. We also argue that this chaotic behavior of the flow has crucial consequences for the dynamics of important processes in the blood, such as the activation of platelets which are involved in the thrombus formation.
| Original language | English |
|---|---|
| Article number | 016213 |
| Number of pages | 7 |
| Journal | Physical Review. E, Statistical, Nonlinear and Soft Matter Physics |
| Volume | 80 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 29 Jul 2009 |
Keywords
- Von-Willebrand-Factor
- shear-stress
- platelet deposition
- hemodynamic factors
- self-association
- abdominal-aorta
- model
- atherosclerosis
- attractors
- activation