Characterisation of mono- and biphasic calcium phosphates granules

S Ke, I R Gibson, K A Hing

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In the present paper 3 different materials, hydroxyapatite (HA), biphasic calcium phosphate (BCP) and tricalcium phosphate (beta-TCP) were synthesised and processed into granules. The granules had different size ranges (212mum-500mum, 500mum-1mm and 1-2mm), with comparable morphologies and microstructures but with different phase compositions. The granules were characterised using surface area analysis (BET), XRD, XRF and SEM. XRD patterns showed that both FLA and beta-TCP granules were single phase with no additional phases present, whilst BCP was approximately a 50:50 biphasic mixture of RA and beta-TCP. The granules were then soaked in deionised water and dilute acetic acid solution for different time periods to investigate how the phase composition affected their solubility. The dissolution behaviour of BCP granules was more comparable to single-phase HA that to beta-TCP. The SEM analysis revealed that calcium phosphate crystals were deposited on the surface of the granules as the soaking times were increased.

Original languageEnglish
Title of host publicationBIOCERAMICS 14
EditorsS Brown, I Clarke, P Williams
Place of PublicationZURICH-UETIKON
PublisherTrans Tech Publications Ltd
Pages625-628
Number of pages4
ISBN (Print)0-87849-889-3
Publication statusPublished - 2002
Event14th International Symposium on Ceramics in Medicine (BIOCERAMICS-14) - PALM SPRINGS
Duration: 14 Nov 200117 Nov 2001

Conference

Conference14th International Symposium on Ceramics in Medicine (BIOCERAMICS-14)
CityPALM SPRINGS
Period14/11/0117/11/01

Keywords

  • calcium phosphate
  • hydroxyapatite
  • biphasic
  • beta-TCP
  • granules
  • solubility

Cite this

Ke, S., Gibson, I. R., & Hing, K. A. (2002). Characterisation of mono- and biphasic calcium phosphates granules. In S. Brown, I. Clarke, & P. Williams (Eds.), BIOCERAMICS 14 (pp. 625-628). ZURICH-UETIKON: Trans Tech Publications Ltd.

Characterisation of mono- and biphasic calcium phosphates granules. / Ke, S ; Gibson, I R ; Hing, K A .

BIOCERAMICS 14. ed. / S Brown; I Clarke; P Williams. ZURICH-UETIKON : Trans Tech Publications Ltd, 2002. p. 625-628.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ke, S, Gibson, IR & Hing, KA 2002, Characterisation of mono- and biphasic calcium phosphates granules. in S Brown, I Clarke & P Williams (eds), BIOCERAMICS 14. Trans Tech Publications Ltd, ZURICH-UETIKON, pp. 625-628, 14th International Symposium on Ceramics in Medicine (BIOCERAMICS-14), PALM SPRINGS, 14/11/01.
Ke S, Gibson IR, Hing KA. Characterisation of mono- and biphasic calcium phosphates granules. In Brown S, Clarke I, Williams P, editors, BIOCERAMICS 14. ZURICH-UETIKON: Trans Tech Publications Ltd. 2002. p. 625-628
Ke, S ; Gibson, I R ; Hing, K A . / Characterisation of mono- and biphasic calcium phosphates granules. BIOCERAMICS 14. editor / S Brown ; I Clarke ; P Williams. ZURICH-UETIKON : Trans Tech Publications Ltd, 2002. pp. 625-628
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N2 - In the present paper 3 different materials, hydroxyapatite (HA), biphasic calcium phosphate (BCP) and tricalcium phosphate (beta-TCP) were synthesised and processed into granules. The granules had different size ranges (212mum-500mum, 500mum-1mm and 1-2mm), with comparable morphologies and microstructures but with different phase compositions. The granules were characterised using surface area analysis (BET), XRD, XRF and SEM. XRD patterns showed that both FLA and beta-TCP granules were single phase with no additional phases present, whilst BCP was approximately a 50:50 biphasic mixture of RA and beta-TCP. The granules were then soaked in deionised water and dilute acetic acid solution for different time periods to investigate how the phase composition affected their solubility. The dissolution behaviour of BCP granules was more comparable to single-phase HA that to beta-TCP. The SEM analysis revealed that calcium phosphate crystals were deposited on the surface of the granules as the soaking times were increased.

AB - In the present paper 3 different materials, hydroxyapatite (HA), biphasic calcium phosphate (BCP) and tricalcium phosphate (beta-TCP) were synthesised and processed into granules. The granules had different size ranges (212mum-500mum, 500mum-1mm and 1-2mm), with comparable morphologies and microstructures but with different phase compositions. The granules were characterised using surface area analysis (BET), XRD, XRF and SEM. XRD patterns showed that both FLA and beta-TCP granules were single phase with no additional phases present, whilst BCP was approximately a 50:50 biphasic mixture of RA and beta-TCP. The granules were then soaked in deionised water and dilute acetic acid solution for different time periods to investigate how the phase composition affected their solubility. The dissolution behaviour of BCP granules was more comparable to single-phase HA that to beta-TCP. The SEM analysis revealed that calcium phosphate crystals were deposited on the surface of the granules as the soaking times were increased.

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