Characteristics of Patients in Platform C19, a COVID-19 Research Database Combining Primary Care Electronic Health Record and Patient Reported Information

Brooklyn Stanley, Andrew Davis, Rupert Jones, Steven A. Julious, Dermot Ryan, David Jackson, David M.G. Halpin, Hilary Pinnock, Jennifer K Quint, Kamlesh Khunti, Liam G Heaney, Philip Oliver, Salman Siddiqui, Anu Kemppinen, Francis Appiagyei, Emma-Jane Roberts, Antony Hardjojo, Victoria Carter, Marije van Melle, David Price* (Corresponding Author)Platform C19 committee

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background
Data to better understand and manage the COVID-19 pandemic is urgently needed. However, there are gaps in information stored within even the best routinely-collected electronic health records (EHR) including test results, remote consultations for suspected COVID-19, shielding, physical activity, mental health, and undiagnosed or untested COVID-19 patients. Observational and Pragmatic Research Institute (OPRI) Singapore and Optimum Patient Care (OPC) UK established Platform C19, a 51 research database combining EHR data and bespoke patient questionnaire. We describe the 52 demographics, clinical characteristics, patient behavior, and impact of the COVID-19 pandemic using data within Platform C19.
Methods

EHR data from Platform C19 were extracted from 14 practices across UK participating in the OPC COVID-19 Quality Improvement program on a continuous, monthly basis. Starting 7th 56 August 2020, consenting patients aged 18-85 years were invited in waves to fill an online questionnaire. Descriptive statistics were summarized using all data available up to 22nd 58 January 2021.

Findings

From 129,978 invitees, 31,033 responded. Respondents were predominantly female (59.6%), white (93.5%), and current or ex-smokers (52.6%). Testing for COVID-19 was received by 23.8% of 62 respondents, of which 7.9% received positive results. COVID-19 symptoms lasted ≥4 weeks in 19.5% of COVID-19 positive respondents. Up to 39% respondents reported a negative impact on questions regarding their mental health. Most (67%-76%) respondents with asthma, Chronic Obstructive Pulmonary Disease (COPD), diabetes, heart, or kidney disease reported no change in the condition of their diseases.

Interpretation
Platform C19 will enable research on key questions relating to COVID-19 pandemic not possible using EHR data alone.
Original languageEnglish
Pages (from-to)e0258689
JournalPloS ONE
Volume16
Issue number10
Early online date19 Oct 2021
DOIs
Publication statusPublished - 19 Oct 2021

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