Characteristics of patients preferring once-daily controller therapy for asthma and COPD: A retrospective cohort study

David Price, Amanda J. Lee, Erika J. Sims, Linda Kemp, Elizabeth V. Hillyer, Alison Chisholm, Julie von Ziegenweidt, Angela Williams

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Background:
Patient preference is an important factor when choosing an inhaler device for asthma or chronic obstructive pulmonary disease (COPD).

Aims:
To identify characteristics of patients with asthma or COPD who prefer a once-daily controller medication regimen.

Methods:
This retrospective observational study used electronic patient records and linked outcomes from patient-completed questionnaires in a primary care database. We compared the characteristics of patients indicating a preference for once-daily therapy with those who were unsure or indicating no preference.

Results:
Of 3,731 patients with asthma, 2,174 (58%) were women; the mean age was 46 years (range 2–94). Of 2,138 patients with COPD, 980 (46%) were women; the mean age was 70 years (range 35–98). Approximately half of the patients in each cohort indicated once-daily preference, one-quarter were unsure, and one-quarter did not prefer once-daily therapy. In patients with asthma or COPD, the preference for once-daily controller medication was significantly associated with poor adherence and higher concerns about medication. In asthma, good control and low self-perceived controller medication need were associated with once-daily preference. By contrast, in COPD, a high self-perceived need for controller medication was associated with once-daily preference. There was no significant relationship between once-daily preference and age, sex, disease severity, or exacerbation history.

Conclusions:
Understanding patient preferences may help prescribers to individualise therapy better for asthma and COPD.
Original languageEnglish
Pages (from-to)161-168
Number of pages8
JournalPrimary Care Respiratory Journal
Volume22
Issue number2
DOIs
Publication statusPublished - 4 Mar 2013

Keywords

  • adherence
  • asthma
  • chronic obstructive pulmonary disease
  • once-daily
  • preference
  • retrospective observational study

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