Characteristics of patients preferring once-daily controller therapy for asthma and COPD: A retrospective cohort study

David Price, Amanda J. Lee, Erika J. Sims, Linda Kemp, Elizabeth V. Hillyer, Alison Chisholm, Julie von Ziegenweidt, Angela Williams

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Background:
Patient preference is an important factor when choosing an inhaler device for asthma or chronic obstructive pulmonary disease (COPD).

Aims:
To identify characteristics of patients with asthma or COPD who prefer a once-daily controller medication regimen.

Methods:
This retrospective observational study used electronic patient records and linked outcomes from patient-completed questionnaires in a primary care database. We compared the characteristics of patients indicating a preference for once-daily therapy with those who were unsure or indicating no preference.

Results:
Of 3,731 patients with asthma, 2,174 (58%) were women; the mean age was 46 years (range 2–94). Of 2,138 patients with COPD, 980 (46%) were women; the mean age was 70 years (range 35–98). Approximately half of the patients in each cohort indicated once-daily preference, one-quarter were unsure, and one-quarter did not prefer once-daily therapy. In patients with asthma or COPD, the preference for once-daily controller medication was significantly associated with poor adherence and higher concerns about medication. In asthma, good control and low self-perceived controller medication need were associated with once-daily preference. By contrast, in COPD, a high self-perceived need for controller medication was associated with once-daily preference. There was no significant relationship between once-daily preference and age, sex, disease severity, or exacerbation history.

Conclusions:
Understanding patient preferences may help prescribers to individualise therapy better for asthma and COPD.
Original languageEnglish
Pages (from-to)161-168
Number of pages8
JournalPrimary Care Respiratory Journal
Volume22
Issue number2
DOIs
Publication statusPublished - 4 Mar 2013

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Chronic Obstructive Pulmonary Disease
Cohort Studies
Asthma
Retrospective Studies
Patient Preference
Therapeutics
Nebulizers and Vaporizers
Observational Studies
Primary Health Care
History
Databases
Equipment and Supplies

Keywords

  • adherence
  • asthma
  • chronic obstructive pulmonary disease
  • once-daily
  • preference
  • retrospective observational study

Cite this

Characteristics of patients preferring once-daily controller therapy for asthma and COPD : A retrospective cohort study. / Price, David; Lee, Amanda J.; Sims, Erika J.; Kemp, Linda; Hillyer, Elizabeth V.; Chisholm, Alison; von Ziegenweidt, Julie; Williams, Angela.

In: Primary Care Respiratory Journal, Vol. 22, No. 2, 04.03.2013, p. 161-168.

Research output: Contribution to journalArticle

Price, David ; Lee, Amanda J. ; Sims, Erika J. ; Kemp, Linda ; Hillyer, Elizabeth V. ; Chisholm, Alison ; von Ziegenweidt, Julie ; Williams, Angela. / Characteristics of patients preferring once-daily controller therapy for asthma and COPD : A retrospective cohort study. In: Primary Care Respiratory Journal. 2013 ; Vol. 22, No. 2. pp. 161-168.
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abstract = "Background:Patient preference is an important factor when choosing an inhaler device for asthma or chronic obstructive pulmonary disease (COPD).Aims:To identify characteristics of patients with asthma or COPD who prefer a once-daily controller medication regimen.Methods:This retrospective observational study used electronic patient records and linked outcomes from patient-completed questionnaires in a primary care database. We compared the characteristics of patients indicating a preference for once-daily therapy with those who were unsure or indicating no preference.Results:Of 3,731 patients with asthma, 2,174 (58{\%}) were women; the mean age was 46 years (range 2–94). Of 2,138 patients with COPD, 980 (46{\%}) were women; the mean age was 70 years (range 35–98). Approximately half of the patients in each cohort indicated once-daily preference, one-quarter were unsure, and one-quarter did not prefer once-daily therapy. In patients with asthma or COPD, the preference for once-daily controller medication was significantly associated with poor adherence and higher concerns about medication. In asthma, good control and low self-perceived controller medication need were associated with once-daily preference. By contrast, in COPD, a high self-perceived need for controller medication was associated with once-daily preference. There was no significant relationship between once-daily preference and age, sex, disease severity, or exacerbation history.Conclusions:Understanding patient preferences may help prescribers to individualise therapy better for asthma and COPD.",
keywords = "adherence, asthma, chronic obstructive pulmonary disease, once-daily, preference, retrospective observational study",
author = "David Price and Lee, {Amanda J.} and Sims, {Erika J.} and Linda Kemp and Hillyer, {Elizabeth V.} and Alison Chisholm and {von Ziegenweidt}, Julie and Angela Williams",
note = "Acknowledgements: We thank Annie Burden for her help with statistical analyses and Rob Horne for his input on the study design and analyses. Funding: The study was sponsored by GlaxoSmithKline. The funders had no role in the conduct of the study or interpretation of study results.",
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AU - Price, David

AU - Lee, Amanda J.

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AU - Kemp, Linda

AU - Hillyer, Elizabeth V.

AU - Chisholm, Alison

AU - von Ziegenweidt, Julie

AU - Williams, Angela

N1 - Acknowledgements: We thank Annie Burden for her help with statistical analyses and Rob Horne for his input on the study design and analyses. Funding: The study was sponsored by GlaxoSmithKline. The funders had no role in the conduct of the study or interpretation of study results.

PY - 2013/3/4

Y1 - 2013/3/4

N2 - Background:Patient preference is an important factor when choosing an inhaler device for asthma or chronic obstructive pulmonary disease (COPD).Aims:To identify characteristics of patients with asthma or COPD who prefer a once-daily controller medication regimen.Methods:This retrospective observational study used electronic patient records and linked outcomes from patient-completed questionnaires in a primary care database. We compared the characteristics of patients indicating a preference for once-daily therapy with those who were unsure or indicating no preference.Results:Of 3,731 patients with asthma, 2,174 (58%) were women; the mean age was 46 years (range 2–94). Of 2,138 patients with COPD, 980 (46%) were women; the mean age was 70 years (range 35–98). Approximately half of the patients in each cohort indicated once-daily preference, one-quarter were unsure, and one-quarter did not prefer once-daily therapy. In patients with asthma or COPD, the preference for once-daily controller medication was significantly associated with poor adherence and higher concerns about medication. In asthma, good control and low self-perceived controller medication need were associated with once-daily preference. By contrast, in COPD, a high self-perceived need for controller medication was associated with once-daily preference. There was no significant relationship between once-daily preference and age, sex, disease severity, or exacerbation history.Conclusions:Understanding patient preferences may help prescribers to individualise therapy better for asthma and COPD.

AB - Background:Patient preference is an important factor when choosing an inhaler device for asthma or chronic obstructive pulmonary disease (COPD).Aims:To identify characteristics of patients with asthma or COPD who prefer a once-daily controller medication regimen.Methods:This retrospective observational study used electronic patient records and linked outcomes from patient-completed questionnaires in a primary care database. We compared the characteristics of patients indicating a preference for once-daily therapy with those who were unsure or indicating no preference.Results:Of 3,731 patients with asthma, 2,174 (58%) were women; the mean age was 46 years (range 2–94). Of 2,138 patients with COPD, 980 (46%) were women; the mean age was 70 years (range 35–98). Approximately half of the patients in each cohort indicated once-daily preference, one-quarter were unsure, and one-quarter did not prefer once-daily therapy. In patients with asthma or COPD, the preference for once-daily controller medication was significantly associated with poor adherence and higher concerns about medication. In asthma, good control and low self-perceived controller medication need were associated with once-daily preference. By contrast, in COPD, a high self-perceived need for controller medication was associated with once-daily preference. There was no significant relationship between once-daily preference and age, sex, disease severity, or exacerbation history.Conclusions:Understanding patient preferences may help prescribers to individualise therapy better for asthma and COPD.

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