Clinical outcomes from a randomised comparison of Microwave Endometrial Ablation with Thermal Balloon endometrial ablation for the treatment of heavy menstrual bleeding

A M Sambrook, K G Cooper, M K Campbell, J A Cook

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Objective  To compare the clinical outcomes of microwave endometrial ablation and thermal balloon ablation for the treatment of heavy menstrual bleeding.Design  A double blind randomised controlled trial.Setting  A UK teaching hospital.Population  Three hundred and twenty women requesting endometrial ablation.Methods  Operative data collection and patient completed postal questionnaires were used to ascertain women’s satisfaction with outcome, acceptability of each procedure, changes in menstrual symptoms and health related quality of life and additional treatments received.Main outcome measures  Primary outcomes were satisfaction and menstrual scores 1 year. Secondary outcomes were operative differences, acceptability of treatment and changes in health related quality of life.Results  Both technologies achieved high levels of satisfaction (−1%, 95% CI (−11, 9)). Menstrual scores were also similar (4%, 95% CI (−7, 19)) Microwave had a significantly shorter operating time, reduced usage of antiemetics and opiate analgesia, increased discharge by 6 hours and fewer device failures.Conclusions  Both treatments are acceptable to women, with high levels of satisfaction. Microwave is quicker to perform with faster hospital discharge.

Original languageEnglish
Pages (from-to)1038-1045
Number of pages8
JournalBJOG-An International Journal of Obstetrics and Gynaecology
Issue number8
Early online date11 May 2009
Publication statusPublished - Jul 2009


  • menorrhagia
  • randomised trial
  • surgical treatments
  • quality-of-life
  • controlled-trial
  • rollerball electroablation
  • abdominal hysterectomy
  • satisfaction rate
  • resection
  • destruction
  • efficacy

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