Cluster analysis according to biomarker profile differentiates clinical subgroups in the International Severe Asthma Registry (ISAR)

Eve Denton, Mark Hew, Trung N. Tran, G. Walter Canonica, Andrew Menzies-Gow, J. Mark FitzGerald, Mohsen Sadatsafavi, Luis Perez, George Christoff, Anna Quinton, Chin Kook Rhee, Guy Brusselle, Charlotte Ulrik, Njira Lugogo, Isha Chaudhry, Lakmini Bulathsinhala, Ruth B. Murray, Victoria A. Carter, David B. Price

Research output: Contribution to conferenceAbstract

Abstract

Background
Inflammatory biomarkers are used to guide severe asthma therapy and may also identify activation of underlying inflammatory pathways. We examined biomarker profiles [immunoglobin E (IgE), blood eosinophils, and fractional exhaled nitric oxide (FeNO)] in a severe asthma cohort by employing both conventional cut-off values and cluster analysis.
Original languageEnglish
Publication statusAccepted/In press - 19 Mar 2020
EventRespiratory Effectiveness Group Summit 2020 -
Duration: 19 Mar 202021 Mar 2020

Conference

ConferenceRespiratory Effectiveness Group Summit 2020
Period19/03/2021/03/20

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  • Cite this

    Denton, E., Hew, M., Tran, T. N., Canonica, G. W., Menzies-Gow, A., FitzGerald, J. M., Sadatsafavi, M., Perez, L., Christoff, G., Quinton, A., Rhee, C. K., Brusselle, G., Ulrik, C., Lugogo, N., Chaudhry, I., Bulathsinhala, L., Murray, R. B., Carter, V. A., & Price, D. B. (Accepted/In press). Cluster analysis according to biomarker profile differentiates clinical subgroups in the International Severe Asthma Registry (ISAR). Abstract from Respiratory Effectiveness Group Summit 2020, .