Cofactor NAD(P)H Regeneration: How Selective Are the Reactions?

Joseph W.H. Burnett, Russell F. Howe, Xiaodong Wang*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

7 Citations (Scopus)


The regeneration of NAD(P)H can be achieved via catalysis, but the unequivocal determination of the species involved has not yet been fully realized. The current analytical methods of reactant/product analysis based on UV-vis spectroscopy, enzymatic assays, NMR spectroscopy, and HPLC are critically examined here with suggestions for future development.

Original languageEnglish
Pages (from-to)488-492
Number of pages5
JournalTrends in Chemistry
Issue number6
Publication statusPublished - Jun 2020


  • analytical methods
  • cofactor regeneration
  • conversion
  • mass balance
  • selectivity


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