Abstract
Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49-63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences.
Original language | English |
---|---|
Pages (from-to) | 91-96 |
Number of pages | 6 |
Journal | Behavior Genetics |
Volume | 44 |
Issue number | 2 |
Early online date | 20 Feb 2014 |
DOIs | |
Publication status | Published - Mar 2014 |
Keywords
- height
- intelligence
- molecular genetics
- genetic correlation
- Generation Scotland
- Scottish family health
- heritability
- metaanalysis
- association
- pleiotrpy
- childhood
- disease
- samples
- cohort