Comparative effectiveness of beta-interferons and glatiramer acetate for relapsing-remitting multiple sclerosis: systematic review and network meta-analysis of trials including recommended dosages

G. J. Melendez-Torres (Corresponding Author), Xavier Armoiry, Rachel Court, Jacoby Patterson, Alan Kan, Peter Auguste, Jason Madan, Carl Counsell, Olga Ciccarelli, Aileen Clarke

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Abstract

We systematically reviewed the comparative effectiveness of injectable beta-interferons (IFN-β) and glatiramer acetate (GA) on annualised relapse rate (ARR), progression and discontinuation due to adverse events (AEs) in RRMS, using evidence from within the drugs’ recommended dosages.
Original languageEnglish
Article number162
JournalBMC Neurology
Volume18
DOIs
Publication statusPublished - 3 Oct 2018

Keywords

  • multiple sclerosis
  • clinically isolated syndrome
  • beta-interferon
  • glatiramer acetate
  • systematic review
  • economic evaluation

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