Abstract
Objective. AAA distensibility (Ep, beta) may predict growth and risk of rupture, However, distensibility measurements based on brachial rather than central pressure may be inaccurate. Our aim was to compare AAA distensibility using non-invasive brachial and derived central aortic pressure.
Design: brachial and central pressures were measured prospectively by automated sphygmomanometry (Omron) and pulse wave analysis (SphygmoCor) respectively. AAA distensibility was calculated using brachial (Ep(b), beta (b)) and central (Ep(c), beta (c)) pressures by ultrasonic echo-tracking (Diamove), Twenty-eight patients (18 males) were selected on a first come basis from a larger study of AAA patients. There were no exclusion criteria, so 54% had cardiac dysfunction (MI, angina) and 14% were hypertensive (BP > 140/90 mmHg).
Results: median (IQR) age was 74 (70-77) years, median AAA (IQR) diameter was 44 (40-51) min. Central and brachial systolic pressures were significantly different, [140 (121-153) vs 144 (130-164) mmHg respectively, p less than or equal to0.01]. Central and brachial diastolic pressures were not significantly different [76 (72-86) vs 76 (71-86) mmHg respectively, p=0.5]. Ey(c) (3.0, [2.2-4.9]) and beta (c) (22.2 [15.5-33.2]) were significantly lower than Ep(b) (3.6, [2.4-5.1] 10(5)Nm(-2)) and beta (b) (24.7 [17.1-33.0] a.u., all p <0.001. Brachial and central derived distensibility remained significantly different after adjusting for age and diameter (p<0.001).
Conclusion: the use of brachial pressure leads to a small, systematic overestimate of Ep (18%) and <beta> (11%) independent of age and AAA diameter. This systematic error will not bias follow-up of changes in distensibility.
| Original language | English |
|---|---|
| Pages (from-to) | 355-360 |
| Number of pages | 5 |
| Journal | European Journal of Vascular and Endovascular Surgery |
| Volume | 22 |
| DOIs | |
| Publication status | Published - 2001 |
Keywords
- abdominal aortic aneurysm
- blood pressure
- distensibility
- ELASTIC PROPERTIES
- STIFFNESS
- DIAMETER
- SEX
- AGE
Cite this
Comparison of brachial artery pressure and derived central pressure in the measurement of abdominal aortic aneurysm distensibility. / Wilson, K. A.; MacCallum, H.; Wilkinson, I. B.; Hoskins, P. R.; Lee, Amanda Jane; Bradbury, A. W.
In: European Journal of Vascular and Endovascular Surgery, Vol. 22, 2001, p. 355-360.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of brachial artery pressure and derived central pressure in the measurement of abdominal aortic aneurysm distensibility
AU - Wilson, K. A.
AU - MacCallum, H.
AU - Wilkinson, I. B.
AU - Hoskins, P. R.
AU - Lee, Amanda Jane
AU - Bradbury, A. W.
PY - 2001
Y1 - 2001
N2 - Objective. AAA distensibility (Ep, beta) may predict growth and risk of rupture, However, distensibility measurements based on brachial rather than central pressure may be inaccurate. Our aim was to compare AAA distensibility using non-invasive brachial and derived central aortic pressure.Design: brachial and central pressures were measured prospectively by automated sphygmomanometry (Omron) and pulse wave analysis (SphygmoCor) respectively. AAA distensibility was calculated using brachial (Ep(b), beta (b)) and central (Ep(c), beta (c)) pressures by ultrasonic echo-tracking (Diamove), Twenty-eight patients (18 males) were selected on a first come basis from a larger study of AAA patients. There were no exclusion criteria, so 54% had cardiac dysfunction (MI, angina) and 14% were hypertensive (BP > 140/90 mmHg).Results: median (IQR) age was 74 (70-77) years, median AAA (IQR) diameter was 44 (40-51) min. Central and brachial systolic pressures were significantly different, [140 (121-153) vs 144 (130-164) mmHg respectively, p less than or equal to0.01]. Central and brachial diastolic pressures were not significantly different [76 (72-86) vs 76 (71-86) mmHg respectively, p=0.5]. Ey(c) (3.0, [2.2-4.9]) and beta (c) (22.2 [15.5-33.2]) were significantly lower than Ep(b) (3.6, [2.4-5.1] 10(5)Nm(-2)) and beta (b) (24.7 [17.1-33.0] a.u., all p <0.001. Brachial and central derived distensibility remained significantly different after adjusting for age and diameter (p<0.001).Conclusion: the use of brachial pressure leads to a small, systematic overestimate of Ep (18%) and (11%) independent of age and AAA diameter. This systematic error will not bias follow-up of changes in distensibility.
AB - Objective. AAA distensibility (Ep, beta) may predict growth and risk of rupture, However, distensibility measurements based on brachial rather than central pressure may be inaccurate. Our aim was to compare AAA distensibility using non-invasive brachial and derived central aortic pressure.Design: brachial and central pressures were measured prospectively by automated sphygmomanometry (Omron) and pulse wave analysis (SphygmoCor) respectively. AAA distensibility was calculated using brachial (Ep(b), beta (b)) and central (Ep(c), beta (c)) pressures by ultrasonic echo-tracking (Diamove), Twenty-eight patients (18 males) were selected on a first come basis from a larger study of AAA patients. There were no exclusion criteria, so 54% had cardiac dysfunction (MI, angina) and 14% were hypertensive (BP > 140/90 mmHg).Results: median (IQR) age was 74 (70-77) years, median AAA (IQR) diameter was 44 (40-51) min. Central and brachial systolic pressures were significantly different, [140 (121-153) vs 144 (130-164) mmHg respectively, p less than or equal to0.01]. Central and brachial diastolic pressures were not significantly different [76 (72-86) vs 76 (71-86) mmHg respectively, p=0.5]. Ey(c) (3.0, [2.2-4.9]) and beta (c) (22.2 [15.5-33.2]) were significantly lower than Ep(b) (3.6, [2.4-5.1] 10(5)Nm(-2)) and beta (b) (24.7 [17.1-33.0] a.u., all p <0.001. Brachial and central derived distensibility remained significantly different after adjusting for age and diameter (p<0.001).Conclusion: the use of brachial pressure leads to a small, systematic overestimate of Ep (18%) and (11%) independent of age and AAA diameter. This systematic error will not bias follow-up of changes in distensibility.
KW - abdominal aortic aneurysm
KW - blood pressure
KW - distensibility
KW - ELASTIC PROPERTIES
KW - STIFFNESS
KW - DIAMETER
KW - SEX
KW - AGE
U2 - 10.1053/ejvs.2001.1465
DO - 10.1053/ejvs.2001.1465
M3 - Article
VL - 22
SP - 355
EP - 360
JO - European Journal of Vascular and Endovascular Surgery
JF - European Journal of Vascular and Endovascular Surgery
SN - 1078-5884
ER -