Conservation and divergence in cellulosome architecture between two strains of Ruminococcus flavefaciens

Sadanari Jindou, Ilya Borovok, Marco T. Rincon, Harry James Flint, Dionysios A. Antonopoulos, Margret E. Berg, Bryan A. White, Edward A. Bayer, Raphael Lamed

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48 Citations (Scopus)


A 17-kb scaffoldin gene cluster in Ruminococcus flavefaciens strain FD-1 was compared with the homologous segment published for strain 17. Although the general design of the cluster is identical in the two strains, significant differences in the modular architecture of the scaffoldin proteins were discovered, implying strain-specific divergence in cellulosome organization.

Original languageEnglish
Pages (from-to)7971-7976
Number of pages6
JournalJournal of Bacteriology
Issue number22
Publication statusPublished - Nov 2006


  • protein
  • Ruminococcus flavefaciens 17
  • organization
  • scaffoldin
  • cellulase
  • sequences
  • bacteria
  • cohesin
  • genes

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