Contraction of polymer gels created by the activity of molecular motors

Mattia Bacca* (Corresponding Author), Omar A. Saleh, Robert M. McMeeking

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We propose a theory based on non-equilibrium thermodynamics to describe the mechanical behavior of an active polymer gel created by the inclusion of molecular motors in its solvent. When activated, these motors attach to the chains of the polymer network and shorten them creating a global contraction of the gel, which mimics the active behavior of a cytoskeleton. The power generated by these motors is obtained by an ATP hydrolysis reaction, which transduces chemical energy into mechanical work. The latter is described by an increment of strain energy in the gel due to an increased stiffness. This effect is described with an increment of the cross-link density in the polymer network, which reduces its entropy. The theory then considers polymer network swelling and species diffusion to describe the transient passive behavior of the gel. We finally formulate the problem of uniaxial contraction of a slab of gel and compare the results with experiments, showing good agreement.

Original languageEnglish
Pages (from-to)4467-4475
Number of pages9
JournalSoft matter
Volume15
Issue number22
Early online date21 May 2019
DOIs
Publication statusPublished - 14 Jun 2019

Fingerprint

contraction
Polymers
Gels
gels
polymers
species diffusion
chemical energy
nonequilibrium thermodynamics
adenosine triphosphate
Strain energy
swelling
Swelling
hydrolysis
Hydrolysis
stiffness
slabs
Entropy
Adenosine Triphosphate
Stiffness
Thermodynamics

Keywords

  • polymer gels
  • molecular motors
  • Thermodynamics

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics

Cite this

Contraction of polymer gels created by the activity of molecular motors. / Bacca, Mattia (Corresponding Author); Saleh, Omar A.; McMeeking, Robert M.

In: Soft matter, Vol. 15, No. 22, 14.06.2019, p. 4467-4475.

Research output: Contribution to journalArticle

Bacca, Mattia ; Saleh, Omar A. ; McMeeking, Robert M. / Contraction of polymer gels created by the activity of molecular motors. In: Soft matter. 2019 ; Vol. 15, No. 22. pp. 4467-4475.
@article{c4703775ab7445618da9b33fe02309b1,
title = "Contraction of polymer gels created by the activity of molecular motors",
abstract = "We propose a theory based on non-equilibrium thermodynamics to describe the mechanical behavior of an active polymer gel created by the inclusion of molecular motors in its solvent. When activated, these motors attach to the chains of the polymer network and shorten them creating a global contraction of the gel, which mimics the active behavior of a cytoskeleton. The power generated by these motors is obtained by an ATP hydrolysis reaction, which transduces chemical energy into mechanical work. The latter is described by an increment of strain energy in the gel due to an increased stiffness. This effect is described with an increment of the cross-link density in the polymer network, which reduces its entropy. The theory then considers polymer network swelling and species diffusion to describe the transient passive behavior of the gel. We finally formulate the problem of uniaxial contraction of a slab of gel and compare the results with experiments, showing good agreement.",
keywords = "polymer gels, molecular motors, Thermodynamics",
author = "Mattia Bacca and Saleh, {Omar A.} and McMeeking, {Robert M.}",
note = "Theoretical calculations were supported by the Natural Science and Engineering Research Council of Canada (NSERC), under the Discovery Grant. Computations were supported by the Institute for Computing, Information and Cognitive Systems (ICICS), at the University of British Columbia. Comparison to experiments was supported by the U.S. Department of Energy (DOE), Office of Science, Basic Energy Sciences (BES) under Award DESC0014427.",
year = "2019",
month = "6",
day = "14",
doi = "10.1039/c8sm02598c",
language = "English",
volume = "15",
pages = "4467--4475",
journal = "Soft matter",
issn = "1744-683X",
publisher = "ROYAL SOC CHEMISTRY",
number = "22",

}

TY - JOUR

T1 - Contraction of polymer gels created by the activity of molecular motors

AU - Bacca, Mattia

AU - Saleh, Omar A.

AU - McMeeking, Robert M.

N1 - Theoretical calculations were supported by the Natural Science and Engineering Research Council of Canada (NSERC), under the Discovery Grant. Computations were supported by the Institute for Computing, Information and Cognitive Systems (ICICS), at the University of British Columbia. Comparison to experiments was supported by the U.S. Department of Energy (DOE), Office of Science, Basic Energy Sciences (BES) under Award DESC0014427.

PY - 2019/6/14

Y1 - 2019/6/14

N2 - We propose a theory based on non-equilibrium thermodynamics to describe the mechanical behavior of an active polymer gel created by the inclusion of molecular motors in its solvent. When activated, these motors attach to the chains of the polymer network and shorten them creating a global contraction of the gel, which mimics the active behavior of a cytoskeleton. The power generated by these motors is obtained by an ATP hydrolysis reaction, which transduces chemical energy into mechanical work. The latter is described by an increment of strain energy in the gel due to an increased stiffness. This effect is described with an increment of the cross-link density in the polymer network, which reduces its entropy. The theory then considers polymer network swelling and species diffusion to describe the transient passive behavior of the gel. We finally formulate the problem of uniaxial contraction of a slab of gel and compare the results with experiments, showing good agreement.

AB - We propose a theory based on non-equilibrium thermodynamics to describe the mechanical behavior of an active polymer gel created by the inclusion of molecular motors in its solvent. When activated, these motors attach to the chains of the polymer network and shorten them creating a global contraction of the gel, which mimics the active behavior of a cytoskeleton. The power generated by these motors is obtained by an ATP hydrolysis reaction, which transduces chemical energy into mechanical work. The latter is described by an increment of strain energy in the gel due to an increased stiffness. This effect is described with an increment of the cross-link density in the polymer network, which reduces its entropy. The theory then considers polymer network swelling and species diffusion to describe the transient passive behavior of the gel. We finally formulate the problem of uniaxial contraction of a slab of gel and compare the results with experiments, showing good agreement.

KW - polymer gels

KW - molecular motors

KW - Thermodynamics

UR - http://www.scopus.com/inward/record.url?scp=85066937410&partnerID=8YFLogxK

UR - http://www.mendeley.com/research/contraction-polymer-gels-created-activity-molecular-motors

U2 - 10.1039/c8sm02598c

DO - 10.1039/c8sm02598c

M3 - Article

VL - 15

SP - 4467

EP - 4475

JO - Soft matter

JF - Soft matter

SN - 1744-683X

IS - 22

ER -