Abstract
The title compound, C12H9N3O, is an intermediate in the synthesis of the muscarinic M2 receptor antagonist AFDX-384. The seven-membered ring adopts a boat conformation and the dihedral angle between the planes of the aromatic rings is 41.51 (9)°. In the crystal, molecules are linked into [001] chains of alternating inversion dimers formed by pairs of N - H⋯O hydrogen bonds and pairs of N - H⋯N hydrogen bonds. In both cases, R22(8) loops are generated.
Original language | English |
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Pages (from-to) | o304-o305 |
Number of pages | 2 |
Journal | Acta Crystallographica Section E: Structure Reports Online |
Volume | 71 |
Issue number | 5 |
Early online date | 11 Apr 2015 |
DOIs | |
Publication status | Published - 1 May 2015 |
Keywords
- Boat conformation
- Crystal structure
- Hydrogen bonding
- Pyridobenzodiazepine