Cyclic and acyclic products from the reactions between methyl 3-oxobutanoate and arylhydrazines

James L. Wardell, Jan Skakle, John N. Low, Christopher Glidewell

Research output: Contribution to journalArticle

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Abstract

The molecules of methyl 3-(2-nitrophenylhydrazono) butanoate, C11H13N3O4, (I), and methyl 3-(2,4-dinitrophenylhydrazono) butanoate, C11H12N4O6, ( II), both prepared from methyl 3- oxobutanoate and the corresponding nitrophenylhydrazine, exhibit polarized molecular electronic structures; in each of ( I) and ( II), the molecules are linked into chains by a single C - H center dot center dot center dot O hydrogen bond. The molecules of 5- hydroxy-3- methyl- 1- phenyl- 1H- pyrazole, C10H10N2O, ( III), prepared by the reaction of methyl 3- oxobutanoate and phenylhydrazine, are linked into chains by a single O - H center dot center dot center dot N hydrogen bond. The reaction between methyl 3- oxobutanoate and 3- nitrophenylhydrazine yields 5- hydroxy- 3- methyl- 1-( 3-nitrophenyl)- 1H- pyrazole, ( IV), which when crystallized from acetone yields 4- isopropylidene- 3- methyl- 1-( 3- nitrophenyl)1H- pyrazol- 5( 4H)- one, C13H13N3O3, ( V).

Original languageEnglish
Number of pages6
JournalActa Crystallographica Section C, Crystal Structure Communications
Volume63
DOIs
Publication statusPublished - Aug 2007

Keywords

  • supramolecular structures
  • X-RAY
  • hydrogen
  • nitroanilines
  • bond
  • diffraction

Cite this

Cyclic and acyclic products from the reactions between methyl 3-oxobutanoate and arylhydrazines. / Wardell, James L.; Skakle, Jan; Low, John N.; Glidewell, Christopher.

In: Acta Crystallographica Section C, Crystal Structure Communications, Vol. 63, 08.2007.

Research output: Contribution to journalArticle

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abstract = "The molecules of methyl 3-(2-nitrophenylhydrazono) butanoate, C11H13N3O4, (I), and methyl 3-(2,4-dinitrophenylhydrazono) butanoate, C11H12N4O6, ( II), both prepared from methyl 3- oxobutanoate and the corresponding nitrophenylhydrazine, exhibit polarized molecular electronic structures; in each of ( I) and ( II), the molecules are linked into chains by a single C - H center dot center dot center dot O hydrogen bond. The molecules of 5- hydroxy-3- methyl- 1- phenyl- 1H- pyrazole, C10H10N2O, ( III), prepared by the reaction of methyl 3- oxobutanoate and phenylhydrazine, are linked into chains by a single O - H center dot center dot center dot N hydrogen bond. The reaction between methyl 3- oxobutanoate and 3- nitrophenylhydrazine yields 5- hydroxy- 3- methyl- 1-( 3-nitrophenyl)- 1H- pyrazole, ( IV), which when crystallized from acetone yields 4- isopropylidene- 3- methyl- 1-( 3- nitrophenyl)1H- pyrazol- 5( 4H)- one, C13H13N3O3, ( V).",
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N2 - The molecules of methyl 3-(2-nitrophenylhydrazono) butanoate, C11H13N3O4, (I), and methyl 3-(2,4-dinitrophenylhydrazono) butanoate, C11H12N4O6, ( II), both prepared from methyl 3- oxobutanoate and the corresponding nitrophenylhydrazine, exhibit polarized molecular electronic structures; in each of ( I) and ( II), the molecules are linked into chains by a single C - H center dot center dot center dot O hydrogen bond. The molecules of 5- hydroxy-3- methyl- 1- phenyl- 1H- pyrazole, C10H10N2O, ( III), prepared by the reaction of methyl 3- oxobutanoate and phenylhydrazine, are linked into chains by a single O - H center dot center dot center dot N hydrogen bond. The reaction between methyl 3- oxobutanoate and 3- nitrophenylhydrazine yields 5- hydroxy- 3- methyl- 1-( 3-nitrophenyl)- 1H- pyrazole, ( IV), which when crystallized from acetone yields 4- isopropylidene- 3- methyl- 1-( 3- nitrophenyl)1H- pyrazol- 5( 4H)- one, C13H13N3O3, ( V).

AB - The molecules of methyl 3-(2-nitrophenylhydrazono) butanoate, C11H13N3O4, (I), and methyl 3-(2,4-dinitrophenylhydrazono) butanoate, C11H12N4O6, ( II), both prepared from methyl 3- oxobutanoate and the corresponding nitrophenylhydrazine, exhibit polarized molecular electronic structures; in each of ( I) and ( II), the molecules are linked into chains by a single C - H center dot center dot center dot O hydrogen bond. The molecules of 5- hydroxy-3- methyl- 1- phenyl- 1H- pyrazole, C10H10N2O, ( III), prepared by the reaction of methyl 3- oxobutanoate and phenylhydrazine, are linked into chains by a single O - H center dot center dot center dot N hydrogen bond. The reaction between methyl 3- oxobutanoate and 3- nitrophenylhydrazine yields 5- hydroxy- 3- methyl- 1-( 3-nitrophenyl)- 1H- pyrazole, ( IV), which when crystallized from acetone yields 4- isopropylidene- 3- methyl- 1-( 3- nitrophenyl)1H- pyrazol- 5( 4H)- one, C13H13N3O3, ( V).

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KW - hydrogen

KW - nitroanilines

KW - bond

KW - diffraction

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