DDK links replication and recombination in meiosis

H. Murakami, S. Keeney

Research output: Contribution to journalEditorialpeer-review


Meiosis begins with DNA replication followed by homologous recombination and nuclear divisions. Since programmed DNA double-strand breaks (DSBs) were discovered to initiate meiotic recombination, extensive studies have identified the players required for DSB formation and the chromosomal features that determine DSB frequency and distribution. However, the temporal control of DSB formation, especially coordination with preceding replication, is poorly understood...
Original languageEnglish
Pages (from-to)3621-3622
JournalCell Cycle
Issue number23
Publication statusPublished - 2014


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