Deciphering the rhizosphere microbiome for disease-suppressive bacteria.

Rodrigo Mendes, Marco Kruijt, Irene De Bruijn, Ester Dekkers, Menno van der Voort, Johannes H. M. Schneider, Yvette M. Piceno, Todd Z. DeSantis, Gary L. Andersen, Peter A. H. M. Bakker, Jos M. Raaijmakers

Research output: Contribution to journalArticle

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Abstract

Disease-suppressive soils are exceptional ecosystems in which crop plants suffer less from specific soil-borne pathogens than expected owing to the activities of other soil microorganisms. For most disease-suppressive soils, the microbes and mechanisms involved in pathogen control are unknown. By coupling PhyloChip-based metagenomics of the rhizosphere microbiome with culture-dependent functional analyses, we identified key bacterial taxa and genes involved in suppression of a fungal root pathogen. More than 33,000 bacterial and archaeal species were detected, with Proteobacteria, Firmicutes, and Actinobacteria consistently associated with disease suppression. Members of the ¿-Proteobacteria were shown to have disease-suppressive activity governed by nonribosomal peptide synthetases. Our data indicate that upon attack by a fungal root pathogen, plants can exploit microbial consortia from soil for protection against infections.
Original languageEnglish
Pages (from-to)1097-1100
Number of pages4
JournalScience
Volume332
Issue number6033
DOIs
Publication statusPublished - 27 May 2011

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suppressive soils
rhizosphere
Proteobacteria
soil microorganisms
pathogens
bacteria
Firmicutes
Actinobacteria
ligases
plant pathogens
soil
disease control
peptides
ecosystems
crops
infection
microbiome
genes

Cite this

Mendes, R., Kruijt, M., De Bruijn, I., Dekkers, E., van der Voort, M., Schneider, J. H. M., ... Raaijmakers, J. M. (2011). Deciphering the rhizosphere microbiome for disease-suppressive bacteria. Science, 332(6033), 1097-1100. https://doi.org/10.1126/science.1203980

Deciphering the rhizosphere microbiome for disease-suppressive bacteria. / Mendes, Rodrigo; Kruijt, Marco; De Bruijn, Irene; Dekkers, Ester; van der Voort, Menno; Schneider, Johannes H. M.; Piceno, Yvette M.; DeSantis, Todd Z.; Andersen, Gary L.; Bakker, Peter A. H. M.; Raaijmakers, Jos M.

In: Science, Vol. 332, No. 6033, 27.05.2011, p. 1097-1100.

Research output: Contribution to journalArticle

Mendes, R, Kruijt, M, De Bruijn, I, Dekkers, E, van der Voort, M, Schneider, JHM, Piceno, YM, DeSantis, TZ, Andersen, GL, Bakker, PAHM & Raaijmakers, JM 2011, 'Deciphering the rhizosphere microbiome for disease-suppressive bacteria.', Science, vol. 332, no. 6033, pp. 1097-1100. https://doi.org/10.1126/science.1203980
Mendes R, Kruijt M, De Bruijn I, Dekkers E, van der Voort M, Schneider JHM et al. Deciphering the rhizosphere microbiome for disease-suppressive bacteria. Science. 2011 May 27;332(6033):1097-1100. https://doi.org/10.1126/science.1203980
Mendes, Rodrigo ; Kruijt, Marco ; De Bruijn, Irene ; Dekkers, Ester ; van der Voort, Menno ; Schneider, Johannes H. M. ; Piceno, Yvette M. ; DeSantis, Todd Z. ; Andersen, Gary L. ; Bakker, Peter A. H. M. ; Raaijmakers, Jos M. / Deciphering the rhizosphere microbiome for disease-suppressive bacteria. In: Science. 2011 ; Vol. 332, No. 6033. pp. 1097-1100.
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