TY - JOUR
T1 - Deciphering the rhizosphere microbiome for disease-suppressive bacteria.
AU - Mendes, Rodrigo
AU - Kruijt, Marco
AU - De Bruijn, Irene
AU - Dekkers, Ester
AU - van der Voort, Menno
AU - Schneider, Johannes H. M.
AU - Piceno, Yvette M.
AU - DeSantis, Todd Z.
AU - Andersen, Gary L.
AU - Bakker, Peter A. H. M.
AU - Raaijmakers, Jos M.
PY - 2011/5/27
Y1 - 2011/5/27
N2 - Disease-suppressive soils are exceptional ecosystems in which crop plants suffer less from specific soil-borne pathogens than expected owing to the activities of other soil microorganisms. For most disease-suppressive soils, the microbes and mechanisms involved in pathogen control are unknown. By coupling PhyloChip-based metagenomics of the rhizosphere microbiome with culture-dependent functional analyses, we identified key bacterial taxa and genes involved in suppression of a fungal root pathogen. More than 33,000 bacterial and archaeal species were detected, with Proteobacteria, Firmicutes, and Actinobacteria consistently associated with disease suppression. Members of the ¿-Proteobacteria were shown to have disease-suppressive activity governed by nonribosomal peptide synthetases. Our data indicate that upon attack by a fungal root pathogen, plants can exploit microbial consortia from soil for protection against infections.
AB - Disease-suppressive soils are exceptional ecosystems in which crop plants suffer less from specific soil-borne pathogens than expected owing to the activities of other soil microorganisms. For most disease-suppressive soils, the microbes and mechanisms involved in pathogen control are unknown. By coupling PhyloChip-based metagenomics of the rhizosphere microbiome with culture-dependent functional analyses, we identified key bacterial taxa and genes involved in suppression of a fungal root pathogen. More than 33,000 bacterial and archaeal species were detected, with Proteobacteria, Firmicutes, and Actinobacteria consistently associated with disease suppression. Members of the ¿-Proteobacteria were shown to have disease-suppressive activity governed by nonribosomal peptide synthetases. Our data indicate that upon attack by a fungal root pathogen, plants can exploit microbial consortia from soil for protection against infections.
U2 - 10.1126/science.1203980
DO - 10.1126/science.1203980
M3 - Article
SN - 0036-8075
VL - 332
SP - 1097
EP - 1100
JO - Science
JF - Science
IS - 6033
ER -