Design, construction and use of a large-sample field-cycled PEDRI imager

David J. Lurie*, Margaret A. Foster, David Yeung, James M S Hutchison

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

68 Citations (Scopus)


The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.

Original languageEnglish
Pages (from-to)1877-1886
Number of pages10
JournalPhysics in Medicine and Biology
Issue number7
Publication statusPublished - 30 Jul 1998


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