Design, construction and use of a large-sample field-cycled PEDRI imager

David J. Lurie; Margaret A. Foster; David Yeung; James M S Hutchison

doi:10.1088/0031-9155/43/7/008

Design, construction and use of a large-sample field-cycled PEDRI imager

David J. Lurie^*, Margaret A. Foster, David Yeung, James M S Hutchison

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

69 Citations (Scopus)

Abstract

The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.

Original language	English
Pages (from-to)	1877-1886
Number of pages	10
Journal	Physics in Medicine and Biology
Volume	43
Issue number	7
DOIs	https://doi.org/10.1088/0031-9155/43/7/008
Publication status	Published - 30 Jul 1998

Bibliographical note

We thank Mr E Stevenson, Mr P Mullen and Mr J Carney for help in the construction of the screened room. This work was funded by the Medical Research Council and by the University of Aberdeen.

Access to Document

10.1088/0031-9155/43/7/008

Cite this

@article{74aa14f727874f4cbb32fd1279582dca,

title = "Design, construction and use of a large-sample field-cycled PEDRI imager",

abstract = "The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.",

author = "Lurie, {David J.} and Foster, {Margaret A.} and David Yeung and Hutchison, {James M S}",

note = "We thank Mr E Stevenson, Mr P Mullen and Mr J Carney for help in the construction of the screened room. This work was funded by the Medical Research Council and by the University of Aberdeen. ",

year = "1998",

month = jul,

day = "30",

doi = "10.1088/0031-9155/43/7/008",

language = "English",

volume = "43",

pages = "1877--1886",

journal = "Physics in Medicine and Biology",

issn = "0031-9155",

publisher = "IOP Publishing Ltd.",

number = "7",

}

TY - JOUR

T1 - Design, construction and use of a large-sample field-cycled PEDRI imager

AU - Lurie, David J.

AU - Foster, Margaret A.

AU - Yeung, David

AU - Hutchison, James M S

N1 - We thank Mr E Stevenson, Mr P Mullen and Mr J Carney for help in the construction of the screened room. This work was funded by the Medical Research Council and by the University of Aberdeen.

PY - 1998/7/30

Y1 - 1998/7/30

N2 - The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.

AB - The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.

UR - http://www.scopus.com/inward/record.url?scp=0031813421&partnerID=8YFLogxK

U2 - 10.1088/0031-9155/43/7/008

DO - 10.1088/0031-9155/43/7/008

M3 - Article

C2 - 9703050

AN - SCOPUS:0031813421

SN - 0031-9155

VL - 43

SP - 1877

EP - 1886

JO - Physics in Medicine and Biology

JF - Physics in Medicine and Biology

IS - 7

ER -

Design, construction and use of a large-sample field-cycled PEDRI imager

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this