Determinants of plasma adropin associated with metabolic control and links to lipid and glucose homeostasis

Marietta Sayegh; Andrew Farquharson; Graham Horgan; Stuart R. Gray; Frank Thies; Viren Ranawana; Janice E. Drew

doi:10.1017/S0029665120007314

Determinants of plasma adropin associated with metabolic control and links to lipid and glucose homeostasis

Marietta Sayegh, Andrew Farquharson, Graham Horgan, Stuart R. Gray, Frank Thies, Viren Ranawana, Janice E. Drew

The Rowett Institute of Nutrition and Health

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Abstract

The peptide hormone, adropin, is altered by diet, reduced in obese individuals and associated with improved metabolic health linked to glucose and lipid metabolism, fat oxidation and vascular function(Reference Drew, Reichardt and Williams1,Reference Gao, Stevens and Butler2) . Growing evidence identifies links between circulating adropin levels and regulation of blood glucose and lipids, implicating this hormone in metabolic diseases, such as diabetes and cardiovascular disease (CVD)(Reference Gao, Stevens and Butler2). However, specific determinants influencing circulating adropin are not fully elucidated. This study aimed to identify determinants regulating plasma adropin levels and associations with metabolic control linked to lipid and glucose regulation.

Original language	English
Article number	E745
Journal	Proceedings of the Nutrition Society
Volume	79
Issue number	OCE3
DOIs	https://doi.org/10.1017/S0029665120007314
Publication status	Published - 19 Oct 2020
Event	Nutrition Society Live 2020 - Virtual event Duration: 14 Jul 2020 → 15 Jul 2020 https://www.nutritionsociety.org/events/nutrition-society-live-2020

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title = "Determinants of plasma adropin associated with metabolic control and links to lipid and glucose homeostasis",

abstract = "The peptide hormone, adropin, is altered by diet, reduced in obese individuals and associated with improved metabolic health linked to glucose and lipid metabolism, fat oxidation and vascular function(Reference Drew, Reichardt and Williams1,Reference Gao, Stevens and Butler2) . Growing evidence identifies links between circulating adropin levels and regulation of blood glucose and lipids, implicating this hormone in metabolic diseases, such as diabetes and cardiovascular disease (CVD)(Reference Gao, Stevens and Butler2). However, specific determinants influencing circulating adropin are not fully elucidated. This study aimed to identify determinants regulating plasma adropin levels and associations with metabolic control linked to lipid and glucose regulation.",

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doi = "10.1017/S0029665120007314",

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AU - Sayegh, Marietta

AU - Farquharson, Andrew

AU - Horgan, Graham

AU - Gray, Stuart R.

AU - Thies, Frank

AU - Ranawana, Viren

AU - Drew, Janice E.

PY - 2020/10/19

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Determinants of plasma adropin associated with metabolic control and links to lipid and glucose homeostasis

Abstract

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