Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections

a randomised controlled trial to compare paper-based and web-based modelling experiments

Shaun Patrick Treweek, Ian W Ricketts, Jillian Francis, Martin Eccles, Debbie Bonetti, Nigel B Pitts, Graeme Maclennan, Frank Sullivan, Claire Jones, Mark Weal, Karen Barnett

Research output: Contribution to journalArticle

10 Citations (Scopus)
5 Downloads (Pure)

Abstract

Background
Much implementation research is focused on full-scale trials with little evidence of preceding modelling work. The Medical Research Council Framework for developing and evaluating complex interventions has argued for more and better theoretical and exploratory work prior to a trial as a means of improving intervention development. Intervention modelling experiments (IMEs) are a way of exploring and refining an intervention before moving to a full-scale trial. They do this by delivering key elements of the intervention in a simulation that approximates clinical practice by, for example, presenting general practitioners (GPs) with a clinical scenario about making a treatment decision.

Methods
The current proposal will run a full, web-based IME involving 250 GPs that will advance the methodology of IMEs by directly comparing results with an earlier paper-based IME. Moreover, the web-based IME will evaluate an intervention that can be put into a full-scale trial that aims to reduce antibiotic prescribing for upper respiratory tract infections in primary care. The study will also include a trial of email versus postal invitations to participate.

Discussion
More effective behaviour change interventions are needed and this study will develop one such intervention and a system to model and test future interventions. This system will be applicable to any situation in the National Health Service where behaviour needs to be modified, including interventions aimed directly at the public.

Trial registration
ClinicalTrials (NCT): NCT01206738
Original languageEnglish
Pages (from-to)16
JournalImplementation Science
Volume6
Issue number1
DOIs
Publication statusPublished - 2011

Fingerprint

Inappropriate Prescribing
Respiratory Tract Infections
General Practitioners
Randomized Controlled Trials
Anti-Bacterial Agents
Health Services Needs and Demand
National Health Programs
Biomedical Research
Primary Health Care
Research
Therapeutics

Cite this

Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections : a randomised controlled trial to compare paper-based and web-based modelling experiments. / Treweek, Shaun Patrick; Ricketts, Ian W; Francis, Jillian; Eccles, Martin; Bonetti, Debbie; Pitts, Nigel B; Maclennan, Graeme; Sullivan, Frank; Jones, Claire; Weal, Mark; Barnett, Karen.

In: Implementation Science, Vol. 6, No. 1, 2011, p. 16.

Research output: Contribution to journalArticle

@article{e9f9935a108f434c9e6118a670bce9d4,
title = "Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections: a randomised controlled trial to compare paper-based and web-based modelling experiments",
abstract = "Background Much implementation research is focused on full-scale trials with little evidence of preceding modelling work. The Medical Research Council Framework for developing and evaluating complex interventions has argued for more and better theoretical and exploratory work prior to a trial as a means of improving intervention development. Intervention modelling experiments (IMEs) are a way of exploring and refining an intervention before moving to a full-scale trial. They do this by delivering key elements of the intervention in a simulation that approximates clinical practice by, for example, presenting general practitioners (GPs) with a clinical scenario about making a treatment decision. Methods The current proposal will run a full, web-based IME involving 250 GPs that will advance the methodology of IMEs by directly comparing results with an earlier paper-based IME. Moreover, the web-based IME will evaluate an intervention that can be put into a full-scale trial that aims to reduce antibiotic prescribing for upper respiratory tract infections in primary care. The study will also include a trial of email versus postal invitations to participate. Discussion More effective behaviour change interventions are needed and this study will develop one such intervention and a system to model and test future interventions. This system will be applicable to any situation in the National Health Service where behaviour needs to be modified, including interventions aimed directly at the public. Trial registration ClinicalTrials (NCT): NCT01206738",
author = "Treweek, {Shaun Patrick} and Ricketts, {Ian W} and Jillian Francis and Martin Eccles and Debbie Bonetti and Pitts, {Nigel B} and Graeme Maclennan and Frank Sullivan and Claire Jones and Mark Weal and Karen Barnett",
year = "2011",
doi = "10.1186/1748-5908-6-16",
language = "English",
volume = "6",
pages = "16",
journal = "Implementation Science",
issn = "1748-5908",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections

T2 - a randomised controlled trial to compare paper-based and web-based modelling experiments

AU - Treweek, Shaun Patrick

AU - Ricketts, Ian W

AU - Francis, Jillian

AU - Eccles, Martin

AU - Bonetti, Debbie

AU - Pitts, Nigel B

AU - Maclennan, Graeme

AU - Sullivan, Frank

AU - Jones, Claire

AU - Weal, Mark

AU - Barnett, Karen

PY - 2011

Y1 - 2011

N2 - Background Much implementation research is focused on full-scale trials with little evidence of preceding modelling work. The Medical Research Council Framework for developing and evaluating complex interventions has argued for more and better theoretical and exploratory work prior to a trial as a means of improving intervention development. Intervention modelling experiments (IMEs) are a way of exploring and refining an intervention before moving to a full-scale trial. They do this by delivering key elements of the intervention in a simulation that approximates clinical practice by, for example, presenting general practitioners (GPs) with a clinical scenario about making a treatment decision. Methods The current proposal will run a full, web-based IME involving 250 GPs that will advance the methodology of IMEs by directly comparing results with an earlier paper-based IME. Moreover, the web-based IME will evaluate an intervention that can be put into a full-scale trial that aims to reduce antibiotic prescribing for upper respiratory tract infections in primary care. The study will also include a trial of email versus postal invitations to participate. Discussion More effective behaviour change interventions are needed and this study will develop one such intervention and a system to model and test future interventions. This system will be applicable to any situation in the National Health Service where behaviour needs to be modified, including interventions aimed directly at the public. Trial registration ClinicalTrials (NCT): NCT01206738

AB - Background Much implementation research is focused on full-scale trials with little evidence of preceding modelling work. The Medical Research Council Framework for developing and evaluating complex interventions has argued for more and better theoretical and exploratory work prior to a trial as a means of improving intervention development. Intervention modelling experiments (IMEs) are a way of exploring and refining an intervention before moving to a full-scale trial. They do this by delivering key elements of the intervention in a simulation that approximates clinical practice by, for example, presenting general practitioners (GPs) with a clinical scenario about making a treatment decision. Methods The current proposal will run a full, web-based IME involving 250 GPs that will advance the methodology of IMEs by directly comparing results with an earlier paper-based IME. Moreover, the web-based IME will evaluate an intervention that can be put into a full-scale trial that aims to reduce antibiotic prescribing for upper respiratory tract infections in primary care. The study will also include a trial of email versus postal invitations to participate. Discussion More effective behaviour change interventions are needed and this study will develop one such intervention and a system to model and test future interventions. This system will be applicable to any situation in the National Health Service where behaviour needs to be modified, including interventions aimed directly at the public. Trial registration ClinicalTrials (NCT): NCT01206738

U2 - 10.1186/1748-5908-6-16

DO - 10.1186/1748-5908-6-16

M3 - Article

VL - 6

SP - 16

JO - Implementation Science

JF - Implementation Science

SN - 1748-5908

IS - 1

ER -