Development of computerised adaptive testing (CAT) for the EORTC QLQ-C30 dimensions

General approach and initial results for physical functioning

Morten Aa Petersen (Corresponding Author), Mogens Groenvold, Neil K Aaronson, Wei-Chu Chie, Thierry Conroy, Anna Constantini, Peter Fayers, Jorunn Helbostad, Bernhard Holzner, Stein Kaasa, Susanne Singer, Galina Velikova, Teresa Young

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Background
Health-related quality of life (HRQOL) questionnaires should ideally be adapted to the individual patient and at the same time scores should be directly comparable across patients. This is achievable using a computerised adaptive test (CAT). Basing the CAT on an existing instrument enables measurement within an established HRQOL framework and allows backward-compatibility with studies using the original instrument. Because of these advantages the EORTC Quality of Life Group (QLG) has initiated a project to develop a CAT version of the widely used EORTC QLQ-C30.

Methods
We present the EORTC QLG’s strategy for developing a CAT. For each dimension of the EORTC QLQ-C30 our approach includes literature search and conceptualisation, formulation of new items, expert and patient evaluations, field-testing, and psychometric analyses of the items. The strategy is illustrated with the initial results of the development of CAT for physical functioning (PF).

Results
We identified 975 PF items in the literature. Of these, 407 items were deemed relevant, i.e. measured one of the PF aspects measured by the QLQ-C30. Based on these items we developed 86 new items. Review by the EORTC CAT-project group reduced this to 66 items. Based on expert and patient evaluations several items were revised and the list was further reduced to 51 items.

Conclusions
Based on the findings for PF, we believe that our approach will generate item pools that are relevant and appropriate for cancer patients. These will form the basis for a backward-compatible CAT assessing the HRQOL dimensions of the EORTC QLQ-C30.
Original languageEnglish
Pages (from-to)1352-1358
Number of pages7
JournalEuropean Journal of Cancer
Volume46
Issue number8
Early online date16 Mar 2010
DOIs
Publication statusPublished - May 2010

Fingerprint

Quality of Life
Psychometrics
Neoplasms
Surveys and Questionnaires

Keywords

  • computerised adaptive test
  • EORTC QLQ-C30
  • Item response theory
  • Item banking
  • Quality of life

Cite this

Development of computerised adaptive testing (CAT) for the EORTC QLQ-C30 dimensions : General approach and initial results for physical functioning. / Petersen, Morten Aa (Corresponding Author); Groenvold, Mogens; Aaronson, Neil K; Chie, Wei-Chu; Conroy, Thierry; Constantini, Anna; Fayers, Peter; Helbostad, Jorunn; Holzner, Bernhard; Kaasa, Stein; Singer, Susanne; Velikova, Galina; Young, Teresa.

In: European Journal of Cancer, Vol. 46, No. 8, 05.2010, p. 1352-1358.

Research output: Contribution to journalArticle

Petersen, MA, Groenvold, M, Aaronson, NK, Chie, W-C, Conroy, T, Constantini, A, Fayers, P, Helbostad, J, Holzner, B, Kaasa, S, Singer, S, Velikova, G & Young, T 2010, 'Development of computerised adaptive testing (CAT) for the EORTC QLQ-C30 dimensions: General approach and initial results for physical functioning', European Journal of Cancer, vol. 46, no. 8, pp. 1352-1358. https://doi.org/10.1016/j.ejca.2010.02.011
Petersen, Morten Aa ; Groenvold, Mogens ; Aaronson, Neil K ; Chie, Wei-Chu ; Conroy, Thierry ; Constantini, Anna ; Fayers, Peter ; Helbostad, Jorunn ; Holzner, Bernhard ; Kaasa, Stein ; Singer, Susanne ; Velikova, Galina ; Young, Teresa. / Development of computerised adaptive testing (CAT) for the EORTC QLQ-C30 dimensions : General approach and initial results for physical functioning. In: European Journal of Cancer. 2010 ; Vol. 46, No. 8. pp. 1352-1358.
@article{8e219808275a403b87fbd68da6721de1,
title = "Development of computerised adaptive testing (CAT) for the EORTC QLQ-C30 dimensions: General approach and initial results for physical functioning",
abstract = "BackgroundHealth-related quality of life (HRQOL) questionnaires should ideally be adapted to the individual patient and at the same time scores should be directly comparable across patients. This is achievable using a computerised adaptive test (CAT). Basing the CAT on an existing instrument enables measurement within an established HRQOL framework and allows backward-compatibility with studies using the original instrument. Because of these advantages the EORTC Quality of Life Group (QLG) has initiated a project to develop a CAT version of the widely used EORTC QLQ-C30.MethodsWe present the EORTC QLG’s strategy for developing a CAT. For each dimension of the EORTC QLQ-C30 our approach includes literature search and conceptualisation, formulation of new items, expert and patient evaluations, field-testing, and psychometric analyses of the items. The strategy is illustrated with the initial results of the development of CAT for physical functioning (PF).ResultsWe identified 975 PF items in the literature. Of these, 407 items were deemed relevant, i.e. measured one of the PF aspects measured by the QLQ-C30. Based on these items we developed 86 new items. Review by the EORTC CAT-project group reduced this to 66 items. Based on expert and patient evaluations several items were revised and the list was further reduced to 51 items.ConclusionsBased on the findings for PF, we believe that our approach will generate item pools that are relevant and appropriate for cancer patients. These will form the basis for a backward-compatible CAT assessing the HRQOL dimensions of the EORTC QLQ-C30.",
keywords = "computerised adaptive test, EORTC QLQ-C30, Item response theory, Item banking, Quality of life",
author = "Petersen, {Morten Aa} and Mogens Groenvold and Aaronson, {Neil K} and Wei-Chu Chie and Thierry Conroy and Anna Constantini and Peter Fayers and Jorunn Helbostad and Bernhard Holzner and Stein Kaasa and Susanne Singer and Galina Velikova and Teresa Young",
note = "Acknowledgement This study was funded by grants from the EORTC Quality of Life Group",
year = "2010",
month = "5",
doi = "10.1016/j.ejca.2010.02.011",
language = "English",
volume = "46",
pages = "1352--1358",
journal = "European Journal of Cancer",
issn = "0959-8049",
publisher = "ELSEVIER APPL SCI PUBL LTD",
number = "8",

}

TY - JOUR

T1 - Development of computerised adaptive testing (CAT) for the EORTC QLQ-C30 dimensions

T2 - General approach and initial results for physical functioning

AU - Petersen, Morten Aa

AU - Groenvold, Mogens

AU - Aaronson, Neil K

AU - Chie, Wei-Chu

AU - Conroy, Thierry

AU - Constantini, Anna

AU - Fayers, Peter

AU - Helbostad, Jorunn

AU - Holzner, Bernhard

AU - Kaasa, Stein

AU - Singer, Susanne

AU - Velikova, Galina

AU - Young, Teresa

N1 - Acknowledgement This study was funded by grants from the EORTC Quality of Life Group

PY - 2010/5

Y1 - 2010/5

N2 - BackgroundHealth-related quality of life (HRQOL) questionnaires should ideally be adapted to the individual patient and at the same time scores should be directly comparable across patients. This is achievable using a computerised adaptive test (CAT). Basing the CAT on an existing instrument enables measurement within an established HRQOL framework and allows backward-compatibility with studies using the original instrument. Because of these advantages the EORTC Quality of Life Group (QLG) has initiated a project to develop a CAT version of the widely used EORTC QLQ-C30.MethodsWe present the EORTC QLG’s strategy for developing a CAT. For each dimension of the EORTC QLQ-C30 our approach includes literature search and conceptualisation, formulation of new items, expert and patient evaluations, field-testing, and psychometric analyses of the items. The strategy is illustrated with the initial results of the development of CAT for physical functioning (PF).ResultsWe identified 975 PF items in the literature. Of these, 407 items were deemed relevant, i.e. measured one of the PF aspects measured by the QLQ-C30. Based on these items we developed 86 new items. Review by the EORTC CAT-project group reduced this to 66 items. Based on expert and patient evaluations several items were revised and the list was further reduced to 51 items.ConclusionsBased on the findings for PF, we believe that our approach will generate item pools that are relevant and appropriate for cancer patients. These will form the basis for a backward-compatible CAT assessing the HRQOL dimensions of the EORTC QLQ-C30.

AB - BackgroundHealth-related quality of life (HRQOL) questionnaires should ideally be adapted to the individual patient and at the same time scores should be directly comparable across patients. This is achievable using a computerised adaptive test (CAT). Basing the CAT on an existing instrument enables measurement within an established HRQOL framework and allows backward-compatibility with studies using the original instrument. Because of these advantages the EORTC Quality of Life Group (QLG) has initiated a project to develop a CAT version of the widely used EORTC QLQ-C30.MethodsWe present the EORTC QLG’s strategy for developing a CAT. For each dimension of the EORTC QLQ-C30 our approach includes literature search and conceptualisation, formulation of new items, expert and patient evaluations, field-testing, and psychometric analyses of the items. The strategy is illustrated with the initial results of the development of CAT for physical functioning (PF).ResultsWe identified 975 PF items in the literature. Of these, 407 items were deemed relevant, i.e. measured one of the PF aspects measured by the QLQ-C30. Based on these items we developed 86 new items. Review by the EORTC CAT-project group reduced this to 66 items. Based on expert and patient evaluations several items were revised and the list was further reduced to 51 items.ConclusionsBased on the findings for PF, we believe that our approach will generate item pools that are relevant and appropriate for cancer patients. These will form the basis for a backward-compatible CAT assessing the HRQOL dimensions of the EORTC QLQ-C30.

KW - computerised adaptive test

KW - EORTC QLQ-C30

KW - Item response theory

KW - Item banking

KW - Quality of life

U2 - 10.1016/j.ejca.2010.02.011

DO - 10.1016/j.ejca.2010.02.011

M3 - Article

VL - 46

SP - 1352

EP - 1358

JO - European Journal of Cancer

JF - European Journal of Cancer

SN - 0959-8049

IS - 8

ER -