Developments in understanding and applying prebiotics in research and practice

an ISAPP conference paper

Karen P Scott (Corresponding Author), Roberta Grimaldi, Marla Cunningham, Shahrul Razid Sarbini, Anisha Wijeyesekera, Mimi L.K. Tang, Jetty C-Y Lee, Yu Fung Yau, Juliet Ansell, Stephan Theis, Kaiping Yang, Ravi Menon, Judith Arfsten, Sarmauli Manurung, Vishnupriya Gourineni, Glenn R. Gibson

Research output: Contribution to journalArticle

Abstract

Aims
The concept of using specific dietary components to selectively modulate the gut microbiota to confer a health benefit, defined as prebiotics, originated in 1995. In 2018, a group of scientists met at the International Scientific Association for Probiotics and Prebiotics annual meeting in Singapore to discuss advances in the prebiotic field, focussing on issues affecting functionality, research methodology, and geographical differences.

Methods and Results
The discussion ranged from examining scientific literature supporting the efficacy of established prebiotics, to the prospects for establishing health benefits associated with novel compounds, isolated from different sources.

Conclusions
While many promising candidate prebiotics from across the globe have been highlighted in preliminary research, there are a limited number with both demonstrated mechanism of action and defined health benefits as required to meet the prebiotic definition.

Prebiotics are part of a food industry with increasing market sales, yet there are great disparities in regulations in different countries. Identification and commercialisation of new prebiotics with unique health benefits means that regulation must improve and remain up‐to‐date so as not to risk stifling research with potential health benefits for humans and other animals.

Significance and Impact of Study
This summary of the workshop discussions indicates potential avenues for expanding the range of prebiotic substrates, delivery methods to enhance health benefits for the end consumer, and guidance to better elucidate their activities in human studies.
Original languageEnglish
JournalJournal of Applied Microbiology
Volume0
Issue numberja
Early online date12 Sep 2019
DOIs
Publication statusE-pub ahead of print - 12 Sep 2019

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Prebiotics
Insurance Benefits
Research
Literature
Food Industry
Singapore
Probiotics
Human Activities
Research Design
Education

Keywords

  • Prebiotics
  • ISAPP
  • gut fermentation
  • microbiome
  • health benefits

Cite this

Developments in understanding and applying prebiotics in research and practice : an ISAPP conference paper. / Scott, Karen P (Corresponding Author); Grimaldi, Roberta; Cunningham, Marla; Sarbini, Shahrul Razid; Wijeyesekera, Anisha; Tang, Mimi L.K.; Lee, Jetty C-Y; Yau, Yu Fung; Ansell, Juliet; Theis, Stephan; Yang, Kaiping; Menon, Ravi; Arfsten, Judith; Manurung, Sarmauli; Gourineni, Vishnupriya; Gibson, Glenn R.

In: Journal of Applied Microbiology, Vol. 0, No. ja, 12.09.2019.

Research output: Contribution to journalArticle

Scott, KP, Grimaldi, R, Cunningham, M, Sarbini, SR, Wijeyesekera, A, Tang, MLK, Lee, JC-Y, Yau, YF, Ansell, J, Theis, S, Yang, K, Menon, R, Arfsten, J, Manurung, S, Gourineni, V & Gibson, GR 2019, 'Developments in understanding and applying prebiotics in research and practice: an ISAPP conference paper', Journal of Applied Microbiology, vol. 0, no. ja. https://doi.org/10.1111/jam.14424
Scott, Karen P ; Grimaldi, Roberta ; Cunningham, Marla ; Sarbini, Shahrul Razid ; Wijeyesekera, Anisha ; Tang, Mimi L.K. ; Lee, Jetty C-Y ; Yau, Yu Fung ; Ansell, Juliet ; Theis, Stephan ; Yang, Kaiping ; Menon, Ravi ; Arfsten, Judith ; Manurung, Sarmauli ; Gourineni, Vishnupriya ; Gibson, Glenn R. / Developments in understanding and applying prebiotics in research and practice : an ISAPP conference paper. In: Journal of Applied Microbiology. 2019 ; Vol. 0, No. ja.
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note = "Acknowledgements The International Scientific Association for Probiotics and Prebiotics (ISAPP) is a notfor-profit organisation dedicated to the science of probiotics and prebiotics activity. The Rowett Institute (KPS) receives financial support from the Scottish Government (RESAS). RG was employed by the University of Reading during this work but is now employed at GSK.",
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T1 - Developments in understanding and applying prebiotics in research and practice

T2 - an ISAPP conference paper

AU - Scott, Karen P

AU - Grimaldi, Roberta

AU - Cunningham, Marla

AU - Sarbini, Shahrul Razid

AU - Wijeyesekera, Anisha

AU - Tang, Mimi L.K.

AU - Lee, Jetty C-Y

AU - Yau, Yu Fung

AU - Ansell, Juliet

AU - Theis, Stephan

AU - Yang, Kaiping

AU - Menon, Ravi

AU - Arfsten, Judith

AU - Manurung, Sarmauli

AU - Gourineni, Vishnupriya

AU - Gibson, Glenn R.

N1 - Acknowledgements The International Scientific Association for Probiotics and Prebiotics (ISAPP) is a notfor-profit organisation dedicated to the science of probiotics and prebiotics activity. The Rowett Institute (KPS) receives financial support from the Scottish Government (RESAS). RG was employed by the University of Reading during this work but is now employed at GSK.

PY - 2019/9/12

Y1 - 2019/9/12

N2 - AimsThe concept of using specific dietary components to selectively modulate the gut microbiota to confer a health benefit, defined as prebiotics, originated in 1995. In 2018, a group of scientists met at the International Scientific Association for Probiotics and Prebiotics annual meeting in Singapore to discuss advances in the prebiotic field, focussing on issues affecting functionality, research methodology, and geographical differences.Methods and ResultsThe discussion ranged from examining scientific literature supporting the efficacy of established prebiotics, to the prospects for establishing health benefits associated with novel compounds, isolated from different sources.ConclusionsWhile many promising candidate prebiotics from across the globe have been highlighted in preliminary research, there are a limited number with both demonstrated mechanism of action and defined health benefits as required to meet the prebiotic definition.Prebiotics are part of a food industry with increasing market sales, yet there are great disparities in regulations in different countries. Identification and commercialisation of new prebiotics with unique health benefits means that regulation must improve and remain up‐to‐date so as not to risk stifling research with potential health benefits for humans and other animals.Significance and Impact of StudyThis summary of the workshop discussions indicates potential avenues for expanding the range of prebiotic substrates, delivery methods to enhance health benefits for the end consumer, and guidance to better elucidate their activities in human studies.

AB - AimsThe concept of using specific dietary components to selectively modulate the gut microbiota to confer a health benefit, defined as prebiotics, originated in 1995. In 2018, a group of scientists met at the International Scientific Association for Probiotics and Prebiotics annual meeting in Singapore to discuss advances in the prebiotic field, focussing on issues affecting functionality, research methodology, and geographical differences.Methods and ResultsThe discussion ranged from examining scientific literature supporting the efficacy of established prebiotics, to the prospects for establishing health benefits associated with novel compounds, isolated from different sources.ConclusionsWhile many promising candidate prebiotics from across the globe have been highlighted in preliminary research, there are a limited number with both demonstrated mechanism of action and defined health benefits as required to meet the prebiotic definition.Prebiotics are part of a food industry with increasing market sales, yet there are great disparities in regulations in different countries. Identification and commercialisation of new prebiotics with unique health benefits means that regulation must improve and remain up‐to‐date so as not to risk stifling research with potential health benefits for humans and other animals.Significance and Impact of StudyThis summary of the workshop discussions indicates potential avenues for expanding the range of prebiotic substrates, delivery methods to enhance health benefits for the end consumer, and guidance to better elucidate their activities in human studies.

KW - Prebiotics

KW - ISAPP

KW - gut fermentation

KW - microbiome

KW - health benefits

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UR - http://www.mendeley.com/research/developments-understanding-applying-prebiotics-research-practicean-isapp-conference-paper

U2 - 10.1111/jam.14424

DO - 10.1111/jam.14424

M3 - Article

VL - 0

JO - Journal of Applied Microbiology

JF - Journal of Applied Microbiology

SN - 1364-5072

IS - ja

ER -