Abstract
Vitamin D deficiency has recently been implicated as a possible risk factor in the etiology of numerous diseases, including nonskeletal conditions. In humans, skin synthesis following exposure to UVB is a potent source of vitamin D, but in regions with low UVB, individuals are at risk of vitamin D deficiency. Our objectives were to describe the prevalence of vitamin D deficiency and to investigate determinants of plasma 25-hydroxyvitamin D (25-OHD) concentrations in a high northern latitude country. Detailed dietary, lifestyle, and demographic data were collected for 2235 healthy adults (21-82 y) from Scotland. Plasma 25-OHD was measured by liquid chromatography-tandem MS. Among study participants, 34.5% were severely deficient (25-OHD 40 nmol/L). Among participants who were taking supplements, 21.3% had a May-standardized 25-OHD concentration >50 nmol/L, 54.2% had 25-50 nmol/L, and 24.5% had
Original language | English |
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Pages (from-to) | 1535-1542 |
Number of pages | 8 |
Journal | The Journal of Nutrition |
Volume | 141 |
Issue number | 8 |
Early online date | 22 Jun 2011 |
DOIs | |
Publication status | Published - 1 Aug 2011 |
Keywords
- Adult
- Aged
- Aged, 80 and over
- Chromatography, Liquid
- Diet
- Dietary Supplements
- Female
- Humans
- Life Style
- Male
- Middle Aged
- Prevalence
- Scotland
- Tandem Mass Spectrometry
- Vitamin D
- Vitamin D Deficiency