Dietary fatty acids affecting hepatic metabolism and atherosclerosis: mechanisms unravelled using a proteomics approach

Guillermo Rodriguez Gutierrez, Baukje De Roos

    Research output: Contribution to journalLiterature reviewpeer-review

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    Dietary fatty acids play an important role in the aetiology of coronary heart disease. The effects of dietary fatty acids on lipoprotein metabolism are well. described, but additional or alternative mechanisms relating to potential influence on coronary heart disease are not known. This review describes how proteomics techniques have been used to identify proteins that are differentially regulated by dietary fatty acids. Such proteins may reveal pathways by which dietary fatty acids influence disease risk.

    Original languageEnglish
    Pages (from-to)28-32
    Number of pages5
    JournalGrasas y Aceites
    Issue number1
    Publication statusPublished - 2009


    • atherosclerosis
    • dietary fatty acids
    • extra virgin olive oils
    • hepatic lipid metabolism
    • proteomics
    • conjugated linoleic-acid
    • E-Asterix-3-Leiden transgenic mice
    • early aortic atherosclerosis
    • hypercholesterolemic hamsters
    • myocardial-infarction
    • Mediterranean diet
    • nutrition research
    • serum-cholesterol
    • fish consumption
    • heart-disease

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