Differential involvement of Th17, Th22 and Regulatory T cells in acute atopic dermatitis lesions compared to uninvolved skin and in the evolution/resolution of atopic patch tests

A. D. Ormerod, B. J. Lewis, F. Meredith, L. G. Lawson, R. N. Barker

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Abstract

Background: Recent studies suggest that Th17 cells participate in atopic dermatitis to a lesser degree than psoriasis and points towards Th22 cells critically contributing more to inflammation in the atopic skin lesions. The aim of this study was to investigate the participation of cells of the Th17/Th22 lineage and regulatory Tcells in acute AD lesions, clinically uninvolved AD skin and examine their dynamics in the evolution and resolution of atopic patch tests.
Original languageEnglish
Article numberEP-51
Pages (from-to)56
Number of pages1
JournalBritish Journal of Dermatology
Volume175
Issue numberSuppl. 2
DOIs
Publication statusPublished - Oct 2016
Event20th Anniversary Conference of the British-Skin-Foundation on Skin Deep - 20 Years of Research - London
Duration: 13 Oct 201613 Oct 2016

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