Differential involvement of Th17, Th22 and Regulatory T cells in acute atopic dermatitis lesions compared to uninvolved skin and in the evolution/resolution of atopic patch tests

A. D. Ormerod, B. J. Lewis, F. Meredith, L. G. Lawson, R. N. Barker

Research output: Contribution to journalAbstract

Abstract

Background: Recent studies suggest that Th17 cells participate in atopic dermatitis to a lesser degree than psoriasis and points towards Th22 cells critically contributing more to inflammation in the atopic skin lesions. The aim of this study was to investigate the participation of cells of the Th17/Th22 lineage and regulatory Tcells in acute AD lesions, clinically uninvolved AD skin and examine their dynamics in the evolution and resolution of atopic patch tests.
Original languageEnglish
Article numberEP-51
Pages (from-to)56
Number of pages1
JournalBritish Journal of Dermatology
Volume175
Issue numberSuppl. 2
DOIs
Publication statusPublished - Oct 2016
Event20th Anniversary Conference of the British-Skin-Foundation on Skin Deep - 20 Years of Research - London
Duration: 13 Oct 2016 → …

Cite this

Differential involvement of Th17, Th22 and Regulatory T cells in acute atopic dermatitis lesions compared to uninvolved skin and in the evolution/resolution of atopic patch tests. / Ormerod, A. D.; Lewis, B. J.; Meredith, F.; Lawson, L. G.; Barker, R. N.

In: British Journal of Dermatology, Vol. 175, No. Suppl. 2, EP-51, 10.2016, p. 56.

Research output: Contribution to journalAbstract

@article{7ede4d13d71b43cbb28cb6eff5713989,
title = "Differential involvement of Th17, Th22 and Regulatory T cells in acute atopic dermatitis lesions compared to uninvolved skin and in the evolution/resolution of atopic patch tests",
abstract = "Background: Recent studies suggest that Th17 cells participate in atopic dermatitis to a lesser degree than psoriasis and points towards Th22 cells critically contributing more to inflammation in the atopic skin lesions. The aim of this study was to investigate the participation of cells of the Th17/Th22 lineage and regulatory Tcells in acute AD lesions, clinically uninvolved AD skin and examine their dynamics in the evolution and resolution of atopic patch tests.",
author = "Ormerod, {A. D.} and Lewis, {B. J.} and F. Meredith and Lawson, {L. G.} and Barker, {R. N.}",
year = "2016",
month = "10",
doi = "10.1111/bjd.14911",
language = "English",
volume = "175",
pages = "56",
journal = "British Journal of Dermatology",
issn = "0007-0963",
publisher = "Wiley",
number = "Suppl. 2",

}

TY - JOUR

T1 - Differential involvement of Th17, Th22 and Regulatory T cells in acute atopic dermatitis lesions compared to uninvolved skin and in the evolution/resolution of atopic patch tests

AU - Ormerod, A. D.

AU - Lewis, B. J.

AU - Meredith, F.

AU - Lawson, L. G.

AU - Barker, R. N.

PY - 2016/10

Y1 - 2016/10

N2 - Background: Recent studies suggest that Th17 cells participate in atopic dermatitis to a lesser degree than psoriasis and points towards Th22 cells critically contributing more to inflammation in the atopic skin lesions. The aim of this study was to investigate the participation of cells of the Th17/Th22 lineage and regulatory Tcells in acute AD lesions, clinically uninvolved AD skin and examine their dynamics in the evolution and resolution of atopic patch tests.

AB - Background: Recent studies suggest that Th17 cells participate in atopic dermatitis to a lesser degree than psoriasis and points towards Th22 cells critically contributing more to inflammation in the atopic skin lesions. The aim of this study was to investigate the participation of cells of the Th17/Th22 lineage and regulatory Tcells in acute AD lesions, clinically uninvolved AD skin and examine their dynamics in the evolution and resolution of atopic patch tests.

U2 - 10.1111/bjd.14911

DO - 10.1111/bjd.14911

M3 - Abstract

VL - 175

SP - 56

JO - British Journal of Dermatology

JF - British Journal of Dermatology

SN - 0007-0963

IS - Suppl. 2

M1 - EP-51

ER -