Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines

K Cuschieri; D Brewster; A R W Williams; D Millan; G Murray; S Nicoll; J Imrie; A Hardie; C Graham; H Cubie

doi:10.1038/sj.bjc.6605556

Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines

K Cuschieri, D Brewster, A R W Williams, D Millan, G Murray, S Nicoll, J Imrie, A Hardie, C Graham, H Cubie

Applied Medicine

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Background/metho: This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection.

Results: HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types.

Conclusion: A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.

Original language	English
Pages (from-to)	930-932
Number of pages	3
Journal	British Journal of Cancer
Volume	102
Issue number	5
Early online date	9 Feb 2010
DOIs	https://doi.org/10.1038/sj.bjc.6605556
Publication status	Published - 2 Mar 2010

Keywords

HPV
genotyping
Scotland

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/sj.bjc.6605556

Cite this

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title = "Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines",

abstract = "Background/metho: This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection. Results: HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types. Conclusion: A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.",

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AU - Cuschieri, K

AU - Brewster, D

AU - Williams, A R W

AU - Millan, D

AU - Murray, G

AU - Nicoll, S

AU - Imrie, J

AU - Hardie, A

AU - Graham, C

AU - Cubie, H

PY - 2010/3/2

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N2 - Background/metho: This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection. Results: HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types. Conclusion: A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.

AB - Background/metho: This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection. Results: HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types. Conclusion: A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.

KW - HPV

KW - genotyping

KW - Scotland

U2 - 10.1038/sj.bjc.6605556

DO - 10.1038/sj.bjc.6605556

M3 - Article

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JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 5

ER -

Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines

Abstract

Keywords

UN SDGs

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