Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines

K Cuschieri, D Brewster, A R W Williams, D Millan, G Murray, S Nicoll, J Imrie, A Hardie, C Graham, H Cubie

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background/metho: This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection.

Results: HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types.

Conclusion: A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.
Original languageEnglish
Pages (from-to)930-932
Number of pages3
JournalBritish Journal of Cancer
Volume102
Issue number5
Early online date9 Feb 2010
DOIs
Publication statusPublished - 2 Mar 2010

Keywords

  • HPV
  • genotyping
  • Scotland

Fingerprint Dive into the research topics of 'Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines'. Together they form a unique fingerprint.

  • Cite this

    Cuschieri, K., Brewster, D., Williams, A. R. W., Millan, D., Murray, G., Nicoll, S., Imrie, J., Hardie, A., Graham, C., & Cubie, H. (2010). Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines. British Journal of Cancer, 102(5), 930-932. https://doi.org/10.1038/sj.bjc.6605556