Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines

K Cuschieri, D Brewster, A R W Williams, D Millan, G Murray, S Nicoll, J Imrie, A Hardie, C Graham, H Cubie

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background/metho: This study evaluated human papillomavirus (HPV) type prevalence in 370 Scottish invasive cervical cancers (ICCs) using HPV genotyping and HPV mRNA detection.

Results: HPV 16 and/or 18 was detected in 72% of cancers overall and in 82% of HPV-positive cancers. HPV 45 and 16 were the most frequently transcribed types.

Conclusion: A significant reduction in ICC in Scotland should be achieved through the HPV immunisation programme.
Original languageEnglish
Pages (from-to)930-932
Number of pages3
JournalBritish Journal of Cancer
Volume102
Issue number5
Early online date9 Feb 2010
DOIs
Publication statusPublished - 2 Mar 2010

Fingerprint

Papillomavirus Vaccines
Scotland
Uterine Cervical Neoplasms
Human papillomavirus 16
Human papillomavirus 18
Immunization Programs
Neoplasms
Messenger RNA

Keywords

  • HPV
  • genotyping
  • Scotland

Cite this

Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines. / Cuschieri, K; Brewster, D; Williams, A R W; Millan, D; Murray, G; Nicoll, S; Imrie, J; Hardie, A; Graham, C; Cubie, H.

In: British Journal of Cancer, Vol. 102, No. 5, 02.03.2010, p. 930-932.

Research output: Contribution to journalArticle

Cuschieri, K, Brewster, D, Williams, ARW, Millan, D, Murray, G, Nicoll, S, Imrie, J, Hardie, A, Graham, C & Cubie, H 2010, 'Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines', British Journal of Cancer, vol. 102, no. 5, pp. 930-932. https://doi.org/10.1038/sj.bjc.6605556
Cuschieri, K ; Brewster, D ; Williams, A R W ; Millan, D ; Murray, G ; Nicoll, S ; Imrie, J ; Hardie, A ; Graham, C ; Cubie, H. / Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines. In: British Journal of Cancer. 2010 ; Vol. 102, No. 5. pp. 930-932.
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