Do men develop type 2 diabetes at lower body mass indices than women?

J Logue, J J Walker, H M Colhoun, G P Leese, R S Lindsay, J A McKnight, A D Morris, D W Pearson, J R Petrie, S Philip, S H Wild, N Sattar, Scottish Diabetes Research Network (SDRN) Epidemiology group

Research output: Contribution to journalArticlepeer-review

148 Citations (Scopus)

Abstract

AIMS/HYPOTHESIS:To describe the associations between age, sex and BMI at diagnosis of type 2 diabetes, and test the hypothesis that men are diagnosed with diabetes at lower average BMI than women of similar age.
METHODS: Linear regression was used to estimate and compare the relationship between age and BMI at diagnosis among 51,920 men and 43,137 women included in a population-based diabetes register in Scotland for whom an index BMI measurement was taken within 1 year of diabetes diagnosis. We also examined HbA(1c) values by sex within the same timescale.
RESULTS: Mean BMI closest to date of diagnosis of type 2 diabetes mellitus was 31.83 kg/m(2) (SD 5.13) in men and 33.69 kg/m(2) (SD 6.43) in women. The inverse relationship between age and BMI at diagnosis of type 2 diabetes mellitus was significantly steeper in women than in men (slope estimate in men -0.12 kg/m(2) per year [95% CI -0.13, -0.12] women -0.18 kg/m(2) per year [95% CI -0.18, -0.17]
Original languageEnglish
Pages (from-to)3003-3006
Number of pages4
JournalDiabetologia
Volume54
Issue number12
DOIs
Publication statusPublished - Dec 2011

Keywords

  • body mass index
  • diagnosis
  • insulin resistance
  • sex

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