Do mirror neuron areas mediate mu rhythm suppression during imitation and action observation?

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Mu rhythm is an EEG measure of resting motor neurons, which is normally suppressed by input because of action observation or movement execution. This characteristic has caused mu suppression to be used as proxy marker for mirror neuron activation. However, there is little direct evidence that fluctuations in mu rhythm suppression reflect concurrent fluctuations in mirror neuron activity. A manual imitation paradigm was used to look at correlations between mu rhythm and BOLD response, by recording sequential EEG and fMRI measures to allow within-subject correlation analyses. Participants were instructed to imitate or observe actions involving the movement of a handle with their right hand. Mu power modulation, defined as mu power changes between conditions, correlated negatively with BOLD response in right inferior parietal lobe, premotor cortex and inferior frontal gyrus; putative mirror neuron areas. Clusters were also identified in bilateral cerebellum, left medial frontal gyrus, right temporal lobe and thalamus. This suggests that mu suppression involves a range of structures that modulate motor preparation activities and are sensitive to visual input, including but not restricted to the human analogue of the mirror neuron system.
Original languageEnglish
Pages (from-to)99-105
Number of pages7
JournalInternational Journal of Psychophysiology
Volume89
Issue number1
Early online date10 Jun 2013
DOIs
Publication statusPublished - Jul 2013

Fingerprint

Mirror Neurons
Observation
Prefrontal Cortex
Electroencephalography
Parietal Lobe
Motor Cortex
Motor Neurons
Proxy
Temporal Lobe
Thalamus
Cerebellum
Motor Activity
Hand
Magnetic Resonance Imaging

Keywords

  • mirror neurons
  • fMRI
  • EEG
  • Mu rhythm

Cite this

@article{e8ddd8bb76834f9d80795ce79fddc641,
title = "Do mirror neuron areas mediate mu rhythm suppression during imitation and action observation?",
abstract = "Mu rhythm is an EEG measure of resting motor neurons, which is normally suppressed by input because of action observation or movement execution. This characteristic has caused mu suppression to be used as proxy marker for mirror neuron activation. However, there is little direct evidence that fluctuations in mu rhythm suppression reflect concurrent fluctuations in mirror neuron activity. A manual imitation paradigm was used to look at correlations between mu rhythm and BOLD response, by recording sequential EEG and fMRI measures to allow within-subject correlation analyses. Participants were instructed to imitate or observe actions involving the movement of a handle with their right hand. Mu power modulation, defined as mu power changes between conditions, correlated negatively with BOLD response in right inferior parietal lobe, premotor cortex and inferior frontal gyrus; putative mirror neuron areas. Clusters were also identified in bilateral cerebellum, left medial frontal gyrus, right temporal lobe and thalamus. This suggests that mu suppression involves a range of structures that modulate motor preparation activities and are sensitive to visual input, including but not restricted to the human analogue of the mirror neuron system.",
keywords = "mirror neurons, fMRI, EEG, Mu rhythm",
author = "Lieke Braadbaart and Williams, {Justin H. G.} and Waiter, {Gordon D.}",
year = "2013",
month = "7",
doi = "10.1016/j.ijpsycho.2013.05.019",
language = "English",
volume = "89",
pages = "99--105",
journal = "International Journal of Psychophysiology",
issn = "0167-8760",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Do mirror neuron areas mediate mu rhythm suppression during imitation and action observation?

AU - Braadbaart, Lieke

AU - Williams, Justin H. G.

AU - Waiter, Gordon D.

PY - 2013/7

Y1 - 2013/7

N2 - Mu rhythm is an EEG measure of resting motor neurons, which is normally suppressed by input because of action observation or movement execution. This characteristic has caused mu suppression to be used as proxy marker for mirror neuron activation. However, there is little direct evidence that fluctuations in mu rhythm suppression reflect concurrent fluctuations in mirror neuron activity. A manual imitation paradigm was used to look at correlations between mu rhythm and BOLD response, by recording sequential EEG and fMRI measures to allow within-subject correlation analyses. Participants were instructed to imitate or observe actions involving the movement of a handle with their right hand. Mu power modulation, defined as mu power changes between conditions, correlated negatively with BOLD response in right inferior parietal lobe, premotor cortex and inferior frontal gyrus; putative mirror neuron areas. Clusters were also identified in bilateral cerebellum, left medial frontal gyrus, right temporal lobe and thalamus. This suggests that mu suppression involves a range of structures that modulate motor preparation activities and are sensitive to visual input, including but not restricted to the human analogue of the mirror neuron system.

AB - Mu rhythm is an EEG measure of resting motor neurons, which is normally suppressed by input because of action observation or movement execution. This characteristic has caused mu suppression to be used as proxy marker for mirror neuron activation. However, there is little direct evidence that fluctuations in mu rhythm suppression reflect concurrent fluctuations in mirror neuron activity. A manual imitation paradigm was used to look at correlations between mu rhythm and BOLD response, by recording sequential EEG and fMRI measures to allow within-subject correlation analyses. Participants were instructed to imitate or observe actions involving the movement of a handle with their right hand. Mu power modulation, defined as mu power changes between conditions, correlated negatively with BOLD response in right inferior parietal lobe, premotor cortex and inferior frontal gyrus; putative mirror neuron areas. Clusters were also identified in bilateral cerebellum, left medial frontal gyrus, right temporal lobe and thalamus. This suggests that mu suppression involves a range of structures that modulate motor preparation activities and are sensitive to visual input, including but not restricted to the human analogue of the mirror neuron system.

KW - mirror neurons

KW - fMRI

KW - EEG

KW - Mu rhythm

U2 - 10.1016/j.ijpsycho.2013.05.019

DO - 10.1016/j.ijpsycho.2013.05.019

M3 - Article

VL - 89

SP - 99

EP - 105

JO - International Journal of Psychophysiology

JF - International Journal of Psychophysiology

SN - 0167-8760

IS - 1

ER -