Dobutamine magnetic resonance imaging as a predictor of myocardial functional recovery after revascularisation

R J Trent, G D Waiter, G S Hillis, F I McKiddie, T W Redpath, S Walton

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objective-To assess the use of dobutamine magnetic resonance imaging (MRI) as a preoperative predictor of myocardial functional recovery after revascularisation, comparing wall motion and radial wall thickening analyses by observer and semi-automated edge detection.

Patients-25 men with multivessel coronary disease and resting wall motion abnormalities were studied with preoperative rest and stress MRI.

Main outcome measures-Observer analysis for radial wall thickening was compared with a normal range, while wall motion analysis used a standard four Feint scale. Semi-automated analysis was performed using an edge detection algorithm. Segments displaying either improved or worsened thickening or motion with dobutamine were considered viable. Postoperative rest images were performed 3-6 months after coronary artery bypass grafting (CABG) for comparison.

Results-For observer analysis the values for sensitivity and specificity were 50% and 72% for wall motion, with respective values of 50% and 68% for thickening. With semi-automated edge detection the figures for motion were 60% and 73%, with corresponding values of 79% and 58% for thickening. Combining thickening and motion for the semi-automated method to describe any change in segmental function yielded a sensitivity of 71% and specificity of 70%.

Conclusions-Dobutamine MRI is a reasonably good predictor of myocardial functional recovery after CABG. The use of semi-automated edge detection analysis improved results.

Original languageEnglish
Pages (from-to)40-46
Number of pages7
JournalHeart
Volume83
Publication statusPublished - 2000

Keywords

  • dobutamine
  • magnetic resonance imaging myocardial viability
  • coronary artery bypass grafting
  • CORONARY-ARTERY DISEASE
  • POSITRON EMISSION TOMOGRAPHY
  • LEFT-VENTRICULAR FUNCTION
  • LOW-DOSE DOBUTAMINE
  • SEGMENTED K-SPACE
  • HIBERNATING MYOCARDIUM
  • VIABLE MYOCARDIUM
  • SURGICAL REVASCULARIZATION
  • DYSFUNCTIONAL MYOCARDIUM
  • COMPUTED-TOMOGRAPHY

Cite this

Dobutamine magnetic resonance imaging as a predictor of myocardial functional recovery after revascularisation. / Trent, R J ; Waiter, G D ; Hillis, G S ; McKiddie, F I ; Redpath, T W ; Walton, S .

In: Heart, Vol. 83, 2000, p. 40-46.

Research output: Contribution to journalArticle

@article{47217867f20f4f21aff367019c469b90,
title = "Dobutamine magnetic resonance imaging as a predictor of myocardial functional recovery after revascularisation",
abstract = "Objective-To assess the use of dobutamine magnetic resonance imaging (MRI) as a preoperative predictor of myocardial functional recovery after revascularisation, comparing wall motion and radial wall thickening analyses by observer and semi-automated edge detection.Patients-25 men with multivessel coronary disease and resting wall motion abnormalities were studied with preoperative rest and stress MRI.Main outcome measures-Observer analysis for radial wall thickening was compared with a normal range, while wall motion analysis used a standard four Feint scale. Semi-automated analysis was performed using an edge detection algorithm. Segments displaying either improved or worsened thickening or motion with dobutamine were considered viable. Postoperative rest images were performed 3-6 months after coronary artery bypass grafting (CABG) for comparison.Results-For observer analysis the values for sensitivity and specificity were 50{\%} and 72{\%} for wall motion, with respective values of 50{\%} and 68{\%} for thickening. With semi-automated edge detection the figures for motion were 60{\%} and 73{\%}, with corresponding values of 79{\%} and 58{\%} for thickening. Combining thickening and motion for the semi-automated method to describe any change in segmental function yielded a sensitivity of 71{\%} and specificity of 70{\%}.Conclusions-Dobutamine MRI is a reasonably good predictor of myocardial functional recovery after CABG. The use of semi-automated edge detection analysis improved results.",
keywords = "dobutamine, magnetic resonance imaging myocardial viability, coronary artery bypass grafting, CORONARY-ARTERY DISEASE, POSITRON EMISSION TOMOGRAPHY, LEFT-VENTRICULAR FUNCTION, LOW-DOSE DOBUTAMINE, SEGMENTED K-SPACE, HIBERNATING MYOCARDIUM, VIABLE MYOCARDIUM, SURGICAL REVASCULARIZATION, DYSFUNCTIONAL MYOCARDIUM, COMPUTED-TOMOGRAPHY",
author = "Trent, {R J} and Waiter, {G D} and Hillis, {G S} and McKiddie, {F I} and Redpath, {T W} and S Walton",
year = "2000",
language = "English",
volume = "83",
pages = "40--46",
journal = "Heart",
issn = "1355-6037",
publisher = "BMJ Publishing Group",

}

TY - JOUR

T1 - Dobutamine magnetic resonance imaging as a predictor of myocardial functional recovery after revascularisation

AU - Trent, R J

AU - Waiter, G D

AU - Hillis, G S

AU - McKiddie, F I

AU - Redpath, T W

AU - Walton, S

PY - 2000

Y1 - 2000

N2 - Objective-To assess the use of dobutamine magnetic resonance imaging (MRI) as a preoperative predictor of myocardial functional recovery after revascularisation, comparing wall motion and radial wall thickening analyses by observer and semi-automated edge detection.Patients-25 men with multivessel coronary disease and resting wall motion abnormalities were studied with preoperative rest and stress MRI.Main outcome measures-Observer analysis for radial wall thickening was compared with a normal range, while wall motion analysis used a standard four Feint scale. Semi-automated analysis was performed using an edge detection algorithm. Segments displaying either improved or worsened thickening or motion with dobutamine were considered viable. Postoperative rest images were performed 3-6 months after coronary artery bypass grafting (CABG) for comparison.Results-For observer analysis the values for sensitivity and specificity were 50% and 72% for wall motion, with respective values of 50% and 68% for thickening. With semi-automated edge detection the figures for motion were 60% and 73%, with corresponding values of 79% and 58% for thickening. Combining thickening and motion for the semi-automated method to describe any change in segmental function yielded a sensitivity of 71% and specificity of 70%.Conclusions-Dobutamine MRI is a reasonably good predictor of myocardial functional recovery after CABG. The use of semi-automated edge detection analysis improved results.

AB - Objective-To assess the use of dobutamine magnetic resonance imaging (MRI) as a preoperative predictor of myocardial functional recovery after revascularisation, comparing wall motion and radial wall thickening analyses by observer and semi-automated edge detection.Patients-25 men with multivessel coronary disease and resting wall motion abnormalities were studied with preoperative rest and stress MRI.Main outcome measures-Observer analysis for radial wall thickening was compared with a normal range, while wall motion analysis used a standard four Feint scale. Semi-automated analysis was performed using an edge detection algorithm. Segments displaying either improved or worsened thickening or motion with dobutamine were considered viable. Postoperative rest images were performed 3-6 months after coronary artery bypass grafting (CABG) for comparison.Results-For observer analysis the values for sensitivity and specificity were 50% and 72% for wall motion, with respective values of 50% and 68% for thickening. With semi-automated edge detection the figures for motion were 60% and 73%, with corresponding values of 79% and 58% for thickening. Combining thickening and motion for the semi-automated method to describe any change in segmental function yielded a sensitivity of 71% and specificity of 70%.Conclusions-Dobutamine MRI is a reasonably good predictor of myocardial functional recovery after CABG. The use of semi-automated edge detection analysis improved results.

KW - dobutamine

KW - magnetic resonance imaging myocardial viability

KW - coronary artery bypass grafting

KW - CORONARY-ARTERY DISEASE

KW - POSITRON EMISSION TOMOGRAPHY

KW - LEFT-VENTRICULAR FUNCTION

KW - LOW-DOSE DOBUTAMINE

KW - SEGMENTED K-SPACE

KW - HIBERNATING MYOCARDIUM

KW - VIABLE MYOCARDIUM

KW - SURGICAL REVASCULARIZATION

KW - DYSFUNCTIONAL MYOCARDIUM

KW - COMPUTED-TOMOGRAPHY

M3 - Article

VL - 83

SP - 40

EP - 46

JO - Heart

JF - Heart

SN - 1355-6037

ER -