Abstract
Spatially compressed dual-wavelength Raman spectroscopy allows recording the full Raman spectrum using a detection system with limited spectral range. The common approach is to record the spectra with the two excitation lasers consecutively and then concatenate the full spectrum. However, with this approach, quantitative analysis for process monitoring is not possible as the investigated object may change between the two acquisitions. In this Note, spectral fusion is proposed as a concept to overcome this problem. The sample is illuminated by the two lasers simultaneously, hence leading to an on-chip fusion of the different parts of the Raman spectrum. It is shown that the resulting data are suitable for quantitative evaluation using univariate and multivariate methods. Dual-wavelength Raman fusion spectroscopy offers new opportunities for building highly compact devices for analytical chemistry.
| Original language | English |
|---|---|
| Pages (from-to) | 1764-1767 |
| Number of pages | 4 |
| Journal | Analytical Chemistry |
| Volume | 91 |
| Issue number | 3 |
| Early online date | 10 Jan 2019 |
| DOIs | |
| Publication status | Published - 5 Feb 2019 |
Keywords
- FLUORESCENCE INTERFERENCE
- DIFFERENCE SPECTROSCOPY
- DIMETHYL-SULFOXIDE
- LASER
- DIODE
Cite this
Dual-Wavelength Raman Fusion Spectroscopy. / Kiefer, Johannes.
In: Analytical Chemistry, Vol. 91, No. 3, 05.02.2019, p. 1764-1767.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dual-Wavelength Raman Fusion Spectroscopy
AU - Kiefer, Johannes
N1 - The author thanks Laser 2000 GmbH (Wessling, Germany) for the loan of the dual-wavelength laser source and the fiber probe and Sabine Wagenfeld for technical assistance. Furthermore, financial support from Deutsche Forschungsgemeinschaft (DFG) through grant KI1396/4-1 is gratefully acknowledged.
PY - 2019/2/5
Y1 - 2019/2/5
N2 - Spatially compressed dual-wavelength Raman spectroscopy allows recording the full Raman spectrum using a detection system with limited spectral range. The common approach is to record the spectra with the two excitation lasers consecutively and then concatenate the full spectrum. However, with this approach, quantitative analysis for process monitoring is not possible as the investigated object may change between the two acquisitions. In this Note, spectral fusion is proposed as a concept to overcome this problem. The sample is illuminated by the two lasers simultaneously, hence leading to an on-chip fusion of the different parts of the Raman spectrum. It is shown that the resulting data are suitable for quantitative evaluation using univariate and multivariate methods. Dual-wavelength Raman fusion spectroscopy offers new opportunities for building highly compact devices for analytical chemistry.
AB - Spatially compressed dual-wavelength Raman spectroscopy allows recording the full Raman spectrum using a detection system with limited spectral range. The common approach is to record the spectra with the two excitation lasers consecutively and then concatenate the full spectrum. However, with this approach, quantitative analysis for process monitoring is not possible as the investigated object may change between the two acquisitions. In this Note, spectral fusion is proposed as a concept to overcome this problem. The sample is illuminated by the two lasers simultaneously, hence leading to an on-chip fusion of the different parts of the Raman spectrum. It is shown that the resulting data are suitable for quantitative evaluation using univariate and multivariate methods. Dual-wavelength Raman fusion spectroscopy offers new opportunities for building highly compact devices for analytical chemistry.
KW - FLUORESCENCE INTERFERENCE
KW - DIFFERENCE SPECTROSCOPY
KW - DIMETHYL-SULFOXIDE
KW - LASER
KW - DIODE
U2 - 10.1021/acs.analchem.8b03909
DO - 10.1021/acs.analchem.8b03909
M3 - Article
VL - 91
SP - 1764
EP - 1767
JO - Analytical Chemistry
JF - Analytical Chemistry
SN - 0003-2700
IS - 3
ER -