Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 173-186 |
| Number of pages | 14 |
| Journal | Imaging in Medicine |
| Volume | 1 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Dec 2009 |
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Dynamic contrast-enhanced MRI in cancer. / Gilbert, Fiona J; Ahearn, Trevor S.
In: Imaging in Medicine, Vol. 1, No. 2, 12.2009, p. 173-186.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dynamic contrast-enhanced MRI in cancer
AU - Gilbert, Fiona J
AU - Ahearn, Trevor S
PY - 2009/12
Y1 - 2009/12
N2 - Dynamic contrast-enhanced MRI has been proven to be a valuable technique in cancer imaging. The poorly formed and leaky vessels formed during angiogenesis to supply tumors facilitate an increased uptake of intravenously administered contrast agents in comparison to normal vasculature. The use of mathematical modeling techniques on the change in tumor signal intensity as a function of time provides a valuable insight into the underlying microvasculature of tumors. As an area of active research, the imaging and modeling of dynamic contrast-enhanced MRI data has many challenges. Novel contrast agents and models contribute to a refining of the technique and its application as a diagnostic tool in cancer imaging.
AB - Dynamic contrast-enhanced MRI has been proven to be a valuable technique in cancer imaging. The poorly formed and leaky vessels formed during angiogenesis to supply tumors facilitate an increased uptake of intravenously administered contrast agents in comparison to normal vasculature. The use of mathematical modeling techniques on the change in tumor signal intensity as a function of time provides a valuable insight into the underlying microvasculature of tumors. As an area of active research, the imaging and modeling of dynamic contrast-enhanced MRI data has many challenges. Novel contrast agents and models contribute to a refining of the technique and its application as a diagnostic tool in cancer imaging.
U2 - 10.2217/iim.09.17
DO - 10.2217/iim.09.17
M3 - Article
VL - 1
SP - 173
EP - 186
JO - Imaging in Medicine
JF - Imaging in Medicine
SN - 1755-5191
IS - 2
ER -