Early life programming of energy balance

R. L. Cripps, Z. A. Archer, J. G. Mercer, S. E. Ozanne

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Obesity prevalence is increasing worldwide, leading to increased morbidity, mortality and health care costs due to its role as a key risk factor in many diseases. Early life growth and nutrition has been implicated in determining susceptibility to obesity in both childhood and adulthood; however, the mechanisms underlying this link are poorly understood. A variety of animal models have been established to try and uncover the developmental programming effects of maternal early life nutrition on energy balance regulation and the mechanisms behind them.

Original languageEnglish
Pages (from-to)1203-1204
Number of pages2
JournalBiochemical Society Transactions
Volume35
Issue number5
DOIs
Publication statusPublished - Nov 2007

Keywords

  • breastfeeding
  • early life nutrition
  • energy balance
  • fetal growth
  • obesity
  • programming
  • hypercaloric nutrition
  • hypothalamic neurons
  • body-composition
  • weight-gain
  • leptin
  • overweight
  • growth
  • birth
  • risk

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