Abstract
Obesity prevalence is increasing worldwide, leading to increased morbidity, mortality and health care costs due to its role as a key risk factor in many diseases. Early life growth and nutrition has been implicated in determining susceptibility to obesity in both childhood and adulthood; however, the mechanisms underlying this link are poorly understood. A variety of animal models have been established to try and uncover the developmental programming effects of maternal early life nutrition on energy balance regulation and the mechanisms behind them.
| Original language | English |
|---|---|
| Pages (from-to) | 1203-1204 |
| Number of pages | 2 |
| Journal | Biochemical Society Transactions |
| Volume | 35 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Nov 2007 |
Keywords
- breastfeeding
- early life nutrition
- energy balance
- fetal growth
- obesity
- programming
- hypercaloric nutrition
- hypothalamic neurons
- body-composition
- weight-gain
- leptin
- overweight
- growth
- birth
- risk
