Abstract
An important scientific breakthrough of the 20th century, IVF helped open new horizons in medicine, such as preimplantation genetic diagnosis and embryonic stem-cell therapy. A further contribution of assisted reproduction technology has been the better understanding of reproductive ageing. Data from IVF cycles suggest that there is a fixed time-interval between accelerated decline of fertility and the menopause. This leads to the hypothesis that a significant proportion of asymptomatic women in the early thirties may be at risk of early onset of subfertility. IVF provides a model for the development of ovarian reserve tests, some of which appear promising as potential screening tools for early ovarian ageing in the general population.
Original language | English |
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Pages (from-to) | 1137-1139 |
Number of pages | 2 |
Journal | Human Reproduction |
Volume | 18 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2003 |
Keywords
- IVF
- ovarian ageing
- screening
- IN-VITRO FERTILIZATION
- FOLLICLE-STIMULATING-HORMONE
- CITRATE CHALLENGE TEST
- NATURAL MENOPAUSE
- DOWNS-SYNDROME
- POOR RESPONSE
- FRAGILE-X
- WOMEN
- INFERTILITY
- RESERVE