Economic evaluation of Medically Assisted Reproduction: an educational overview of methods and applications for healthcare professionals

Jeroen  Luyten; Mark P.  Connolly; Evelyn  Verbeke; Klaus  Buhler; Graham Scotland; Monica Lispi; Alberto  Revelli; Isabelle  Borget; Isabelle  Cedrin-Durnerinm; Thomas M. D’hooghe

doi:10.1016/j.bpobgyn.2022.01.008

Economic evaluation of Medically Assisted Reproduction: an educational overview of methods and applications for healthcare professionals

Jeroen Luyten, Mark P. Connolly, Evelyn Verbeke, Klaus Buhler, Graham Scotland, Monica Lispi, Alberto Revelli, Isabelle Borget, Isabelle Cedrin-Durnerinm, Thomas M. D’hooghe^* (Corresponding Author)

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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Abstract

Economic evaluations of the value-for-money of Medically Assisted Reproduction (MAR) interventions are increasingly important due to growing pressure on healthcare budgets. While such evaluations are commonplace in the published literature, the number/methodological complexity of different evaluations available, and the challenges specific to MAR interventions, can complicate the interpretation of such analyses for fertility treatments. This article aims to serve as an educational resource and provide context on the design/interpretation of economic analyses for MAR interventions. Several areas are relevant for first-line providers and decision makers: scope of analysis, comparator used, perspective/time horizon considered, outcomes used to measure success, and how results from cost-effectiveness studies can be summarized and used in clinical practice. We aim to help clinicians better understand the strengths/weaknesses of economic analyses, to enable the best use of the evidence in practice, so resources available for MAR interventions can provide maximum value to patients and society.

Original language	English
Pages (from-to)	217-228
Number of pages	12
Journal	Best Practice & Research Clinical Obstetrics & Gynaecology
Volume	85
Early online date	2 Feb 2022
DOIs	https://doi.org/10.1016/j.bpobgyn.2022.01.008
Publication status	Published - 1 Dec 2022

Bibliographical note

Acknowledgements
Medical writing support was provided by Steven Goodrick of in Science Communications, Springer Healthcare Ltd, UK, and was funded by Merck Healthcare KGaA, Darmstadt, Germany

Data Availability Statement

Data availability
Any requests for data by qualified scientific and medical researchers for legitimate research purposes will be subject to Merck KGaA's Data Sharing Policy. All requests should be submitted in writing to Merck KGaA's data sharing portal https://www.merckgroup.com/en/research/our-approach-to-research-and-development/healthcare/clinical-trials/commitment-responsible-data-sharing.html. When Merck KGaA has a co-research, co-development, or co-marketing or co-promotion agreement, or when the product has been out-licensed, the responsibility for disclosure might be dependent on the agreement between parties. Under these circumstances, Merck KGaA will endeavour to gain agreement to share data in response to requests.

Keywords

Economic evaluation
Assisted reproduction
Cost-effectiveness analysis
Fertility treatment

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Cite this

Luyten, J., Connolly, M. P., Verbeke, E., Buhler, K., Scotland, G., Lispi, M., Revelli, A., Borget, I., Cedrin-Durnerinm, I., & D’hooghe, T. M. (2022). Economic evaluation of Medically Assisted Reproduction: an educational overview of methods and applications for healthcare professionals . Best Practice & Research Clinical Obstetrics & Gynaecology, 85 , 217-228. https://doi.org/10.1016/j.bpobgyn.2022.01.008

Luyten, J, Connolly, MP, Verbeke, E, Buhler, K, Scotland, G, Lispi, M, Revelli, A, Borget, I, Cedrin-Durnerinm, I & D’hooghe, TM 2022, 'Economic evaluation of Medically Assisted Reproduction: an educational overview of methods and applications for healthcare professionals ', Best Practice & Research Clinical Obstetrics & Gynaecology, vol. 85 , pp. 217-228. https://doi.org/10.1016/j.bpobgyn.2022.01.008

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abstract = "Economic evaluations of the value-for-money of Medically Assisted Reproduction (MAR) interventions are increasingly important due to growing pressure on healthcare budgets. While such evaluations are commonplace in the published literature, the number/methodological complexity of different evaluations available, and the challenges specific to MAR interventions, can complicate the interpretation of such analyses for fertility treatments. This article aims to serve as an educational resource and provide context on the design/interpretation of economic analyses for MAR interventions. Several areas are relevant for first-line providers and decision makers: scope of analysis, comparator used, perspective/time horizon considered, outcomes used to measure success, and how results from cost-effectiveness studies can be summarized and used in clinical practice. We aim to help clinicians better understand the strengths/weaknesses of economic analyses, to enable the best use of the evidence in practice, so resources available for MAR interventions can provide maximum value to patients and society.",

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Economic evaluation of Medically Assisted Reproduction: an educational overview of methods and applications for healthcare professionals

Abstract

Bibliographical note

Data Availability Statement

Keywords

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