Effectiveness of intrauterine insemination in subfertile couples with an isolated cervical factor: a randomized clinical trial

Pieternel Steures*, Jan Willem van der Steeg, Peter G.A. Hompes, Patrick M.M. Bossuyt, J. Dik F. Habbema, Marinus J.C. Eijkemans, Willem A. Schöls, Jan M. Burggraaff, Fulco van der Veen, Ben W.J. Mol

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

After randomization of subfertile couples with an isolated cervical factor to intrauterine insemination for 6 months or expectant management for 6 months, 26 women (51%) vs. 16 women (33%) conceived, respectively. Of these pregnancies, 22 (43%) vs. 13 (27%) were ongoing (relative risk, 1.6; 95% confidence interval, 0.91 to 2.8). There was one multiple pregnancy in the group that was allocated to intrauterine insemination. This trial suggests a beneficial effect of IUI in couples with an isolated cervical factor.

Original languageEnglish
Pages (from-to)1692-1696
Number of pages5
JournalFertility and Sterility
Volume88
Issue number6
DOIs
Publication statusPublished - 1 Dec 2007

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