Effects of caffeine in non-withdrawn volunteers

G. Christopher, David McGregor Sutherland, A. P. Smith

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Rationale Evidence for the behavioural effects of caffeine is prevalent in the literature. It is associated with increased subjective alertness, improved reaction time and enhanced encoding of new information. However. there is an on-going debate as to whether such changes are in fact improvements or merely a reversal of the negative effects of caffeine withdrawal. Using participants who had consumed their normal daily quota of caffeine this study alleviated this potential confound as all participants were not withdrawn at the time of testing.
Objectives To determine whether caffeine influenced the mood and performance of non-withdrawn volunteers.
Methods Sixty eight volunteers, all of whom were regular caffeine consumers, consumed their normal amount of caffeine over the course of the day. Baseline measures of mood and performance were then carried out followed by double-blind administration of caffeine (2 mg/kg) or placebo. The test battery was repeated again 30 min after ingestion of the drink.
Results Our findings showed improvements comparable to previous research. Mood was improved and performance on a number of cognitive measures was improved. The findings are discussed in relation to both noradrenergic and cholinergic neurotransmitter systems.
Conclusions This study provided evidence against the argument that behavioural changes due to caffeine are merely the reversal of negative withdrawal effects. Copyright (C) 2004 John Wiley Sons, Ltd.
Original languageEnglish
Pages (from-to)1-7
Number of pages8
JournalHuman Psychopharmacology-Clinical and Experimental
Volume20
Issue number1
Early online date26 Nov 2004
DOIs
Publication statusPublished - Jan 2005

Fingerprint

Caffeine
Volunteers
Nuclear Family
Cholinergic Agents
Reaction Time
Neurotransmitter Agents
Eating
Placebos
Research

Keywords

  • mood
  • caffeine
  • psychomotor performance
  • psychopharmacology
  • consumption
  • abstinence
  • attention
  • arousal
  • memory

Cite this

Effects of caffeine in non-withdrawn volunteers. / Christopher, G.; Sutherland, David McGregor; Smith, A. P.

In: Human Psychopharmacology-Clinical and Experimental, Vol. 20, No. 1, 01.2005, p. 1-7.

Research output: Contribution to journalArticle

@article{6a5822a7a880409698b2c9a6635511f7,
title = "Effects of caffeine in non-withdrawn volunteers",
abstract = "Rationale Evidence for the behavioural effects of caffeine is prevalent in the literature. It is associated with increased subjective alertness, improved reaction time and enhanced encoding of new information. However. there is an on-going debate as to whether such changes are in fact improvements or merely a reversal of the negative effects of caffeine withdrawal. Using participants who had consumed their normal daily quota of caffeine this study alleviated this potential confound as all participants were not withdrawn at the time of testing. Objectives To determine whether caffeine influenced the mood and performance of non-withdrawn volunteers. Methods Sixty eight volunteers, all of whom were regular caffeine consumers, consumed their normal amount of caffeine over the course of the day. Baseline measures of mood and performance were then carried out followed by double-blind administration of caffeine (2 mg/kg) or placebo. The test battery was repeated again 30 min after ingestion of the drink. Results Our findings showed improvements comparable to previous research. Mood was improved and performance on a number of cognitive measures was improved. The findings are discussed in relation to both noradrenergic and cholinergic neurotransmitter systems. Conclusions This study provided evidence against the argument that behavioural changes due to caffeine are merely the reversal of negative withdrawal effects. Copyright (C) 2004 John Wiley Sons, Ltd.",
keywords = "mood, caffeine, psychomotor performance, psychopharmacology, consumption, abstinence, attention, arousal, memory",
author = "G. Christopher and Sutherland, {David McGregor} and Smith, {A. P.}",
year = "2005",
month = "1",
doi = "10.1002/hup.658",
language = "English",
volume = "20",
pages = "1--7",
journal = "Human Psychopharmacology-Clinical and Experimental",
issn = "0885-6222",
publisher = "John Wiley and Sons Ltd",
number = "1",

}

TY - JOUR

T1 - Effects of caffeine in non-withdrawn volunteers

AU - Christopher, G.

AU - Sutherland, David McGregor

AU - Smith, A. P.

PY - 2005/1

Y1 - 2005/1

N2 - Rationale Evidence for the behavioural effects of caffeine is prevalent in the literature. It is associated with increased subjective alertness, improved reaction time and enhanced encoding of new information. However. there is an on-going debate as to whether such changes are in fact improvements or merely a reversal of the negative effects of caffeine withdrawal. Using participants who had consumed their normal daily quota of caffeine this study alleviated this potential confound as all participants were not withdrawn at the time of testing. Objectives To determine whether caffeine influenced the mood and performance of non-withdrawn volunteers. Methods Sixty eight volunteers, all of whom were regular caffeine consumers, consumed their normal amount of caffeine over the course of the day. Baseline measures of mood and performance were then carried out followed by double-blind administration of caffeine (2 mg/kg) or placebo. The test battery was repeated again 30 min after ingestion of the drink. Results Our findings showed improvements comparable to previous research. Mood was improved and performance on a number of cognitive measures was improved. The findings are discussed in relation to both noradrenergic and cholinergic neurotransmitter systems. Conclusions This study provided evidence against the argument that behavioural changes due to caffeine are merely the reversal of negative withdrawal effects. Copyright (C) 2004 John Wiley Sons, Ltd.

AB - Rationale Evidence for the behavioural effects of caffeine is prevalent in the literature. It is associated with increased subjective alertness, improved reaction time and enhanced encoding of new information. However. there is an on-going debate as to whether such changes are in fact improvements or merely a reversal of the negative effects of caffeine withdrawal. Using participants who had consumed their normal daily quota of caffeine this study alleviated this potential confound as all participants were not withdrawn at the time of testing. Objectives To determine whether caffeine influenced the mood and performance of non-withdrawn volunteers. Methods Sixty eight volunteers, all of whom were regular caffeine consumers, consumed their normal amount of caffeine over the course of the day. Baseline measures of mood and performance were then carried out followed by double-blind administration of caffeine (2 mg/kg) or placebo. The test battery was repeated again 30 min after ingestion of the drink. Results Our findings showed improvements comparable to previous research. Mood was improved and performance on a number of cognitive measures was improved. The findings are discussed in relation to both noradrenergic and cholinergic neurotransmitter systems. Conclusions This study provided evidence against the argument that behavioural changes due to caffeine are merely the reversal of negative withdrawal effects. Copyright (C) 2004 John Wiley Sons, Ltd.

KW - mood

KW - caffeine

KW - psychomotor performance

KW - psychopharmacology

KW - consumption

KW - abstinence

KW - attention

KW - arousal

KW - memory

U2 - 10.1002/hup.658

DO - 10.1002/hup.658

M3 - Article

VL - 20

SP - 1

EP - 7

JO - Human Psychopharmacology-Clinical and Experimental

JF - Human Psychopharmacology-Clinical and Experimental

SN - 0885-6222

IS - 1

ER -