Elucigene FH20 and LIPOchip for the diagnosis of familial hypercholesterolaemia: a systematic review and economic evaluation

P Sharma, D Boyers, C Boachie, F Stewart, Z Miedzybrodzka, W Simpson, M Kilonzo, P McNamee, G Mowatt

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Abstract

Familial hypercholesterolemia (FH) is an autosomal dominant genetic condition causing a high risk of coronary heart disease. The prevalence of this disease is about 1 in 500 in the UK, affecting about 120,000 people across the whole of the UK. Current guidelines recommend DNA testing, however, these guidelines are poorly implemented, therefore 102,000 or 85% of this group remain undiagnosed.
Original languageEnglish
Pages (from-to)1-266
Number of pages266
JournalHealth Technology Assessment
Volume16
Issue number17
DOIs
Publication statusPublished - Mar 2012

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Hyperlipoproteinemia Type II
Cost-Benefit Analysis
Guidelines
Dominant Genes
Coronary Disease
DNA

Cite this

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AU - Kilonzo, M

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