Enantioselective Raman spectroscopy (esR) for distinguishing between the enantiomers of 2-butanol

Claudia C. Rullich, Johannes Kiefer*

*Corresponding author for this work

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The first experimental application of enantioselective Raman spectroscopy (esR) is demonstrated using the example of the chiral alcohol 2-butanol. Samples of the neat enantiomers and the racemic mixture were analyzed in a self-built Raman set-up. The Raman spectrum allows the discrimination of the chemical species. It is shown that the optical rotation of a Raman peak with a small depolarization ratio can be measured. In addition, without any sample modification, e.g. chiral solvent, the enantiomers are distinguishable at a suitable half-wave retarder angle detecting only the vertically polarized component of the Raman signal.

Original languageEnglish
Pages (from-to)3040-3048
Number of pages9
JournalAnalyst
Volume143
Issue number13
Early online date16 May 2018
DOIs
Publication statusPublished - 7 Jul 2018

Keywords

  • VIBRATIONAL CIRCULAR-DICHROISM
  • OPTICAL-ACTIVITY SPECTROSCOPY
  • HYDROGEN-BONDED COMPLEXES
  • CHIRAL MOLECULES
  • ABSOLUTE-CONFIGURATIONS
  • MICROWAVE SPECTROSCOPY
  • DISCRIMINATION
  • SCATTERING
  • ALCOHOLS
  • SPECTRA

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