Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea

Pascaline Priou, Frédéric Gagnadoux, Angela Tesse, Maria Letizia Mastronardi, Abdelali Agouni, Nicole Meslier, Jean-Louis Racineux, Maria Carmen Martinez, Wojciech Trzepizur, Ramaroson Andriantsitohaina

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Abstract

Endothelial dysfunction is involved in vascular complications of obstructive sleep apnea (OSA). In this study, circulating microparticles (MPs) from patients with OSA-induced nocturnal desaturations were characterized and their effects on endothelial function were evaluated. Two age-matched groups of patients undergoing polysomnography for OSA were compared: 35 desaturators with a 3% oxyhemoglobin desaturation index (ODI) > or = 10 events per hour of sleep and 27 nondesaturators with ODI
Original languageEnglish
Pages (from-to)974-983
Number of pages10
JournalAmerican Journal of Pathology
Volume177
Issue number2
DOIs
Publication statusPublished - Aug 2010

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Obstructive Sleep Apnea
Oxyhemoglobins
Polysomnography
Blood Vessels
Sleep
Research Design
Age Groups

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Priou, P., Gagnadoux, F., Tesse, A., Mastronardi, M. L., Agouni, A., Meslier, N., ... Andriantsitohaina, R. (2010). Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea. American Journal of Pathology, 177(2), 974-983. https://doi.org/10.2353/ajpath.2010.091252

Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea. / Priou, Pascaline; Gagnadoux, Frédéric; Tesse, Angela; Mastronardi, Maria Letizia; Agouni, Abdelali; Meslier, Nicole; Racineux, Jean-Louis; Martinez, Maria Carmen; Trzepizur, Wojciech; Andriantsitohaina, Ramaroson.

In: American Journal of Pathology, Vol. 177, No. 2, 08.2010, p. 974-983.

Research output: Contribution to journalArticle

Priou, P, Gagnadoux, F, Tesse, A, Mastronardi, ML, Agouni, A, Meslier, N, Racineux, J-L, Martinez, MC, Trzepizur, W & Andriantsitohaina, R 2010, 'Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea', American Journal of Pathology, vol. 177, no. 2, pp. 974-983. https://doi.org/10.2353/ajpath.2010.091252
Priou, Pascaline ; Gagnadoux, Frédéric ; Tesse, Angela ; Mastronardi, Maria Letizia ; Agouni, Abdelali ; Meslier, Nicole ; Racineux, Jean-Louis ; Martinez, Maria Carmen ; Trzepizur, Wojciech ; Andriantsitohaina, Ramaroson. / Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea. In: American Journal of Pathology. 2010 ; Vol. 177, No. 2. pp. 974-983.
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