Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea

Pascaline Priou, Frédéric Gagnadoux, Angela Tesse, Maria Letizia Mastronardi, Abdelali Agouni, Nicole Meslier, Jean-Louis Racineux, Maria Carmen Martinez, Wojciech Trzepizur, Ramaroson Andriantsitohaina

Research output: Contribution to journalArticlepeer-review

66 Citations (Scopus)

Abstract

Endothelial dysfunction is involved in vascular complications of obstructive sleep apnea (OSA). In this study, circulating microparticles (MPs) from patients with OSA-induced nocturnal desaturations were characterized and their effects on endothelial function were evaluated. Two age-matched groups of patients undergoing polysomnography for OSA were compared: 35 desaturators with a 3% oxyhemoglobin desaturation index (ODI) > or = 10 events per hour of sleep and 27 nondesaturators with ODI
Original languageEnglish
Pages (from-to)974-983
Number of pages10
JournalAmerican Journal of Pathology
Volume177
Issue number2
DOIs
Publication statusPublished - Aug 2010

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