TY - JOUR
T1 - Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea
AU - Priou, Pascaline
AU - Gagnadoux, Frédéric
AU - Tesse, Angela
AU - Mastronardi, Maria Letizia
AU - Agouni, Abdelali
AU - Meslier, Nicole
AU - Racineux, Jean-Louis
AU - Martinez, Maria Carmen
AU - Trzepizur, Wojciech
AU - Andriantsitohaina, Ramaroson
PY - 2010/8
Y1 - 2010/8
N2 - Endothelial dysfunction is involved in vascular complications of obstructive sleep apnea (OSA). In this study, circulating microparticles (MPs) from patients with OSA-induced nocturnal desaturations were characterized and their effects on endothelial function were evaluated. Two age-matched groups of patients undergoing polysomnography for OSA were compared: 35 desaturators with a 3% oxyhemoglobin desaturation index (ODI) > or = 10 events per hour of sleep and 27 nondesaturators with ODI
AB - Endothelial dysfunction is involved in vascular complications of obstructive sleep apnea (OSA). In this study, circulating microparticles (MPs) from patients with OSA-induced nocturnal desaturations were characterized and their effects on endothelial function were evaluated. Two age-matched groups of patients undergoing polysomnography for OSA were compared: 35 desaturators with a 3% oxyhemoglobin desaturation index (ODI) > or = 10 events per hour of sleep and 27 nondesaturators with ODI
U2 - 10.2353/ajpath.2010.091252
DO - 10.2353/ajpath.2010.091252
M3 - Article
C2 - 20566740
SN - 0002-9440
VL - 177
SP - 974
EP - 983
JO - American Journal of Pathology
JF - American Journal of Pathology
IS - 2
ER -