Eosinophil overview: structure, biological properties, and key functions

Page Lacy, Helene Rosenberg, Garry Michael Walsh

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Citations (Scopus)

Abstract

The eosinophil is an enigmatic cell with a continuing ability to fascinate. A considerable history of research endeavor on eosinophil biology stretches from the present time back to the nineteenth century. Perhaps one of the most fascinating aspects of the eosinophil is how accumulating knowledge has changed the perception of its function from passive bystander, modulator of inflammation, to potent effector cell loaded with histotoxic substances through to more recent recognition that it can act as both a positive and negative regulator of complex events in both innate and adaptive immunity. This book consists of 26 chapters written by experts in the field of eosinophil biology that provide comprehensive and clearly written protocols for techniques designed to underpin research into the function of the eosinophil in health and disease.
Original languageEnglish
Title of host publicationEosinophils
Subtitle of host publicationMethods and Protocols
EditorsGarry Walsh
Place of PublicationNew York
PublisherSpringer
Pages1-12
Number of pages12
Volume1178
ISBN (Electronic)978-1-4939-1016-8
ISBN (Print)978-1-4939-1015-1
DOIs
Publication statusPublished - 2014

Publication series

NameMethods in Molecular Biology
PublisherSpringer
Volume1178
ISSN (Print)1064-3745

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Keywords

  • eosinophil
  • accumulation
  • apoptosis
  • degranulation
  • animal models

Cite this

Lacy, P., Rosenberg, H., & Walsh, G. M. (2014). Eosinophil overview: structure, biological properties, and key functions. In G. Walsh (Ed.), Eosinophils : Methods and Protocols (Vol. 1178, pp. 1-12). (Methods in Molecular Biology ; Vol. 1178). New York: Springer . https://doi.org/10.1007/978-1-4939-1016-8_1